Mary Wilson
Well-known member
Published online August 23, 2021.
doi:10.1001/jamainternmed.2021.4686
Yang Ge, MS[SUP]1[/SUP]; Leonardo Martinez, PhD[SUP]2[/SUP]; Shengzhi Sun, PhD[SUP]3[/SUP]; et al
Key Points
Question Is there an association between the timing of exposure to and severity of COVID-19 disease in close contacts of index patients with COVID-19?
Findings In this cohort study of 730 index patients with a COVID-19 diagnosis and 8852 close contacts, transmission potential was greatest in the first 2 days before and 3 days after onset of symptoms in the index patient. When contacts received a diagnosis of COVID-19 infection, they were more likely to present asymptomatically if they had been exposed to an asymptomatic patient.
Meaning These results suggest that the quantity of exposure to a patient with COVID-19 may be associated with clinical presentation among close contacts who develop COVID-19.
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2783099
doi:10.1001/jamainternmed.2021.4686
Yang Ge, MS[SUP]1[/SUP]; Leonardo Martinez, PhD[SUP]2[/SUP]; Shengzhi Sun, PhD[SUP]3[/SUP]; et al
Key Points
Question Is there an association between the timing of exposure to and severity of COVID-19 disease in close contacts of index patients with COVID-19?
Findings In this cohort study of 730 index patients with a COVID-19 diagnosis and 8852 close contacts, transmission potential was greatest in the first 2 days before and 3 days after onset of symptoms in the index patient. When contacts received a diagnosis of COVID-19 infection, they were more likely to present asymptomatically if they had been exposed to an asymptomatic patient.
Meaning These results suggest that the quantity of exposure to a patient with COVID-19 may be associated with clinical presentation among close contacts who develop COVID-19.
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2783099