tetano
Editor, Senior Moderator
Cureus
. 2023 Feb 27;15(2):e35530.
doi: 10.7759/cureus.35530. eCollection 2023 Feb.
An Unusual Case of Combined Thrombosis and Amegakaryocytopenia Resembling Thrombosis With Thrombocytopenia Syndrome Following COVID-19 Infection in an Unvaccinated Patient
Mariam Hassan[SUP] 1 [/SUP], Swathi Prakash[SUP] 1 [/SUP], Jose Rayas[SUP] 1 [/SUP], Jared J Bies[SUP] 1 [/SUP], Sukhila Reddy[SUP] 1 [/SUP], Sahithi Nadella[SUP] 1 [/SUP], Sara Alhariri[SUP] 1 [/SUP], Yousf Radwan[SUP] 1 [/SUP], Nawar Hakim[SUP] 2 [/SUP], Javier Corral[SUP] 3 [/SUP]
Affiliations
Abstract
As a global community, we have learned that the manifestations of severe acute respiratory syndrome coronavirus 2 (SAR-CoV-2), infection, or coronavirus disease 2019 (COVID-19), extends far beyond respiratory compromise. Thrombocytopenia is thought to occur secondary to increased platelet consumption. Platelet activation and platelet-mediated immune inflammation contribute towards the thromboembolic complications seen in COVID-19 patients. In this report, the authors present the unusual case of a 75-year-old female with a history of COVID-19 infection who presented with a transient ischemic attack, thrombocytopenia, and amegakaryocytopenia.
Keywords: amegakaryocytopenia; covid 19; heparin induced thrombocytopenia (hit); sars-cov-2 infection; severe acute respiratory syndrome coronavirus-2; thrombosis with thrombocytopenia syndrome (tts); vaccine-induced prothrombotic immune thrombocytopenia (vipit); vaccine-induced thrombotic thrombocytopenia (vitt).
. 2023 Feb 27;15(2):e35530.
doi: 10.7759/cureus.35530. eCollection 2023 Feb.
An Unusual Case of Combined Thrombosis and Amegakaryocytopenia Resembling Thrombosis With Thrombocytopenia Syndrome Following COVID-19 Infection in an Unvaccinated Patient
Mariam Hassan[SUP] 1 [/SUP], Swathi Prakash[SUP] 1 [/SUP], Jose Rayas[SUP] 1 [/SUP], Jared J Bies[SUP] 1 [/SUP], Sukhila Reddy[SUP] 1 [/SUP], Sahithi Nadella[SUP] 1 [/SUP], Sara Alhariri[SUP] 1 [/SUP], Yousf Radwan[SUP] 1 [/SUP], Nawar Hakim[SUP] 2 [/SUP], Javier Corral[SUP] 3 [/SUP]
Affiliations
- PMID: 37007352
- PMCID: PMC10054843
- DOI: 10.7759/cureus.35530
Abstract
As a global community, we have learned that the manifestations of severe acute respiratory syndrome coronavirus 2 (SAR-CoV-2), infection, or coronavirus disease 2019 (COVID-19), extends far beyond respiratory compromise. Thrombocytopenia is thought to occur secondary to increased platelet consumption. Platelet activation and platelet-mediated immune inflammation contribute towards the thromboembolic complications seen in COVID-19 patients. In this report, the authors present the unusual case of a 75-year-old female with a history of COVID-19 infection who presented with a transient ischemic attack, thrombocytopenia, and amegakaryocytopenia.
Keywords: amegakaryocytopenia; covid 19; heparin induced thrombocytopenia (hit); sars-cov-2 infection; severe acute respiratory syndrome coronavirus-2; thrombosis with thrombocytopenia syndrome (tts); vaccine-induced prothrombotic immune thrombocytopenia (vipit); vaccine-induced thrombotic thrombocytopenia (vitt).