tetano
Editor, Senior Moderator
Cureus
. 2022 Mar 6;14(3):e22888.
doi: 10.7759/cureus.22888. eCollection 2022 Mar.
Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study
Vijayashree Thyagaraj[SUP] 1 [/SUP], Akshay Rao[SUP] 1 [/SUP], Ashwin Kulkarni[SUP] 2 [/SUP], Tharanath Shankar[SUP] 3 [/SUP], Nithin R[SUP] 1 [/SUP], Hridya Unnikrishnan[SUP] 1 [/SUP], Keerthi Kalaiah[SUP] 1 [/SUP], Iniya E[SUP] 1 [/SUP], Sundar K Veluswamy[SUP] 4 [/SUP], Nanda Kumar B S[SUP] 5 [/SUP], Savita Ravindra[SUP] 4 [/SUP], Naresh Shetty[SUP] 6 [/SUP]
Affiliations
Abstract
Background: Coronavirus disease 2019 (COVID-19) survivors may continue experiencing diverse symptoms. This study portrays the clinical and laboratory profile of patients with post-acute sequelae of COVID-19'(PASC) at a tertiary care hospital in India. Methodology: This cross-sectional study enrolled patients visiting the post-COVID-19 clinic three weeks after their acute COVID-19 illness. Their clinical, serological, and radiological characteristics were collected and analyzed.
Results: Of the 259 participants (age: 48.02±15.27 years; 62.25% men), 168 had PASC manifestations. The most frequently reported symptoms were fatigue (n=71(42.26%)), breathlessness (n=38(22.61%)), and cough (n=35(20.83%)). Patients with PASC had higher body mass index (28.24±5.02 vs. 26.26±3.65; p=0.002), history of hypertension (52 (30.95%) vs. 17 (18.6%); p=0.039), uncontrolled systolic blood pressure (37 (22.03) vs. 14 (15.38); p=0.042), and persistent chest x-ray abnormalities (34 (20.23) vs. 10 (10.98); p=0.048).
Conclusion: Fatigue, breathlessness, and cough are common PASC symptoms. Hypertension, obesity, and abnormal chest x-ray findings at follow-up are potential risk factors for developing PASC.
Keywords: cough; fatigue; post covid-19 manifestations; post-acute covid-19; post-covid sequelae.
. 2022 Mar 6;14(3):e22888.
doi: 10.7759/cureus.22888. eCollection 2022 Mar.
Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study
Vijayashree Thyagaraj[SUP] 1 [/SUP], Akshay Rao[SUP] 1 [/SUP], Ashwin Kulkarni[SUP] 2 [/SUP], Tharanath Shankar[SUP] 3 [/SUP], Nithin R[SUP] 1 [/SUP], Hridya Unnikrishnan[SUP] 1 [/SUP], Keerthi Kalaiah[SUP] 1 [/SUP], Iniya E[SUP] 1 [/SUP], Sundar K Veluswamy[SUP] 4 [/SUP], Nanda Kumar B S[SUP] 5 [/SUP], Savita Ravindra[SUP] 4 [/SUP], Naresh Shetty[SUP] 6 [/SUP]
Affiliations
- PMID: 35273894
- PMCID: PMC8901080
- DOI: 10.7759/cureus.22888
Abstract
Background: Coronavirus disease 2019 (COVID-19) survivors may continue experiencing diverse symptoms. This study portrays the clinical and laboratory profile of patients with post-acute sequelae of COVID-19'(PASC) at a tertiary care hospital in India. Methodology: This cross-sectional study enrolled patients visiting the post-COVID-19 clinic three weeks after their acute COVID-19 illness. Their clinical, serological, and radiological characteristics were collected and analyzed.
Results: Of the 259 participants (age: 48.02±15.27 years; 62.25% men), 168 had PASC manifestations. The most frequently reported symptoms were fatigue (n=71(42.26%)), breathlessness (n=38(22.61%)), and cough (n=35(20.83%)). Patients with PASC had higher body mass index (28.24±5.02 vs. 26.26±3.65; p=0.002), history of hypertension (52 (30.95%) vs. 17 (18.6%); p=0.039), uncontrolled systolic blood pressure (37 (22.03) vs. 14 (15.38); p=0.042), and persistent chest x-ray abnormalities (34 (20.23) vs. 10 (10.98); p=0.048).
Conclusion: Fatigue, breathlessness, and cough are common PASC symptoms. Hypertension, obesity, and abnormal chest x-ray findings at follow-up are potential risk factors for developing PASC.
Keywords: cough; fatigue; post covid-19 manifestations; post-acute covid-19; post-covid sequelae.