tetano
Editor, Senior Moderator
Cureus
. 2020 Aug 14;12(8):e9731.
doi: 10.7759/cureus.9731.
Diabetic Ketoacidosis in Coronavirus Disease Patients With Type 2 Diabetes Mellitus
Soe P Winn[SUP] 1 2 [/SUP], Zin Thawdar Oo[SUP] 2 [/SUP], Nyein Nyein Htun[SUP] 3 [/SUP], May Hnin Pwint Soe[SUP] 1 [/SUP], May M Aung[SUP] 1 [/SUP]
Affiliations
Abstract
The occurrence of diabetes is increasing globally and carries a variety of complications, such as thromboembolism, acute cerebrovascular accidents, and diabetic ketoacidosis (DKA). Although DKA is not commonly associated with type 2 diabetes (T2D), it can manifest in patients who have underlying comorbidities predisposed to DKA. Since the emergence of the coronavirus disease (COVID-19) pandemic, we have seen many cases and studies on the underlying pathophysiology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia with or without respiratory failure. We have also learned that the angiotensin-converting enzyme receptor is one of the major entry sites of SARS-CoV-2 infection, and it might be one of the causes that predispose patients to DKA. However, few studies exist that explore the development of DKA in T2D with SARS-CoV-2 infection. We present two cases of patients with DKA and COVID-19 treated with an insulin regimen with no further complications.
Keywords: corona virus disease 2019 (covid-19); covid-19; diabetes mellitus; diabetes type 2; diabetic ketoacidosis.
. 2020 Aug 14;12(8):e9731.
doi: 10.7759/cureus.9731.
Diabetic Ketoacidosis in Coronavirus Disease Patients With Type 2 Diabetes Mellitus
Soe P Winn[SUP] 1 2 [/SUP], Zin Thawdar Oo[SUP] 2 [/SUP], Nyein Nyein Htun[SUP] 3 [/SUP], May Hnin Pwint Soe[SUP] 1 [/SUP], May M Aung[SUP] 1 [/SUP]
Affiliations
- PMID: 32953287
- PMCID: PMC7491247
- DOI: 10.7759/cureus.9731
Abstract
The occurrence of diabetes is increasing globally and carries a variety of complications, such as thromboembolism, acute cerebrovascular accidents, and diabetic ketoacidosis (DKA). Although DKA is not commonly associated with type 2 diabetes (T2D), it can manifest in patients who have underlying comorbidities predisposed to DKA. Since the emergence of the coronavirus disease (COVID-19) pandemic, we have seen many cases and studies on the underlying pathophysiology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia with or without respiratory failure. We have also learned that the angiotensin-converting enzyme receptor is one of the major entry sites of SARS-CoV-2 infection, and it might be one of the causes that predispose patients to DKA. However, few studies exist that explore the development of DKA in T2D with SARS-CoV-2 infection. We present two cases of patients with DKA and COVID-19 treated with an insulin regimen with no further complications.
Keywords: corona virus disease 2019 (covid-19); covid-19; diabetes mellitus; diabetes type 2; diabetic ketoacidosis.