tetano
Editor, Senior Moderator
Cureus
. 2021 Jan 14;13(1):e12695.
doi: 10.7759/cureus.12695.
Guillain-Barr? Syndrome as a Complication of COVID-19
Adeel S Zubair[SUP] 1 [/SUP], Aarij S Zubair[SUP] 2 [/SUP], Kunal Desai[SUP] 1 [/SUP], Ahmad Abulaban[SUP] 1 [/SUP], Bhaskar Roy[SUP] 1 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) is associated with multiple neurological complications including Guillain-Barre syndrome (GBS).While there are reports of COVID-19 -related GBS cases, much remain unknown. We report two cases of GBS-associated COVID-19, which started about eight weeks after the initial COVID-19 infection. Such a long duration between infection and symptom onset of GBS is unusual for post-infectious GBS. Moreover, severely ill patients with COVID-19 may have prolonged hospital stay leading to critical illness myoneuropathy. Diagnosing superimposed GBS can be challenging in such cases. Clinical suspicion, nerve conduction studies with electromyography, and cerebrospinal fluid analysis can help in making the correct diagnosis. Both presented cases responded to intravenous immunoglobulin therapy.
Keywords: coronavirus disease 19; covid-19; critical illness myopathy; critical illness polyneuropathy; guillain-barr? syndrome; neurology; neuromuscular disorder.
. 2021 Jan 14;13(1):e12695.
doi: 10.7759/cureus.12695.
Guillain-Barr? Syndrome as a Complication of COVID-19
Adeel S Zubair[SUP] 1 [/SUP], Aarij S Zubair[SUP] 2 [/SUP], Kunal Desai[SUP] 1 [/SUP], Ahmad Abulaban[SUP] 1 [/SUP], Bhaskar Roy[SUP] 1 [/SUP]
Affiliations
- PMID: 33614303
- PMCID: PMC7883582
- DOI: 10.7759/cureus.12695
Abstract
Coronavirus disease 2019 (COVID-19) is associated with multiple neurological complications including Guillain-Barre syndrome (GBS).While there are reports of COVID-19 -related GBS cases, much remain unknown. We report two cases of GBS-associated COVID-19, which started about eight weeks after the initial COVID-19 infection. Such a long duration between infection and symptom onset of GBS is unusual for post-infectious GBS. Moreover, severely ill patients with COVID-19 may have prolonged hospital stay leading to critical illness myoneuropathy. Diagnosing superimposed GBS can be challenging in such cases. Clinical suspicion, nerve conduction studies with electromyography, and cerebrospinal fluid analysis can help in making the correct diagnosis. Both presented cases responded to intravenous immunoglobulin therapy.
Keywords: coronavirus disease 19; covid-19; critical illness myopathy; critical illness polyneuropathy; guillain-barr? syndrome; neurology; neuromuscular disorder.