tetano
Editor, Senior Moderator
Cureus
. 2021 Oct 25;13(10):e19036.
doi: 10.7759/cureus.19036. eCollection 2021 Oct.
Multiple Sclerosis Following SARS-CoV-2 Infection: A Case Report and Literature Review
Sobia Sarwar[SUP] 1 [/SUP], Sylvette Rogers[SUP] 2 [/SUP], Alaa S Mohamed[SUP] 3 [/SUP], Enitare Ogula[SUP] 4 [/SUP], Rihanat A Ayantayo[SUP] 5 [/SUP], Ahmed Ahmed[SUP] 6 [/SUP], Iram Shahzadi[SUP] 7 [/SUP], Saurabh Kataria[SUP] 8 9 10 [/SUP], Romil Singh[SUP] 11 [/SUP]
Affiliations
Abstract
Coronavirus disease 19 (COVID-19) is caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). Apart from respiratory manifestations, COVID-19 can affect the nervous system due to its neurotropic features. Neurological manifestations and complications include headache, polyneuropathies, cerebrovascular accidents, seizures, encephalopathy, and demyelinating disease. We describe a case of multiple sclerosis, a demyelinating disease following COVID-19 infection, rarely reported in the literature. A 47-year-old female presented with fatigue, blurry vision, numbness, and signs of upper motor neuron lesions that had occurred three weeks after COVID-19 infection. Magnetic resonance imaging of the brain revealed demyelinating lesions in the periventricular area of both hemispheres, suggesting a demyelinating disease. A provisional diagnosis of multiple sclerosis was made. Her condition improved after the commencement of methylprednisolone.
Keywords: covid-19; demyelinating diseases; multiple sclerosis; post-covid complications; sars-cov-2.
. 2021 Oct 25;13(10):e19036.
doi: 10.7759/cureus.19036. eCollection 2021 Oct.
Multiple Sclerosis Following SARS-CoV-2 Infection: A Case Report and Literature Review
Sobia Sarwar[SUP] 1 [/SUP], Sylvette Rogers[SUP] 2 [/SUP], Alaa S Mohamed[SUP] 3 [/SUP], Enitare Ogula[SUP] 4 [/SUP], Rihanat A Ayantayo[SUP] 5 [/SUP], Ahmed Ahmed[SUP] 6 [/SUP], Iram Shahzadi[SUP] 7 [/SUP], Saurabh Kataria[SUP] 8 9 10 [/SUP], Romil Singh[SUP] 11 [/SUP]
Affiliations
- PMID: 34858736
- PMCID: PMC8612412
- DOI: 10.7759/cureus.19036
Abstract
Coronavirus disease 19 (COVID-19) is caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). Apart from respiratory manifestations, COVID-19 can affect the nervous system due to its neurotropic features. Neurological manifestations and complications include headache, polyneuropathies, cerebrovascular accidents, seizures, encephalopathy, and demyelinating disease. We describe a case of multiple sclerosis, a demyelinating disease following COVID-19 infection, rarely reported in the literature. A 47-year-old female presented with fatigue, blurry vision, numbness, and signs of upper motor neuron lesions that had occurred three weeks after COVID-19 infection. Magnetic resonance imaging of the brain revealed demyelinating lesions in the periventricular area of both hemispheres, suggesting a demyelinating disease. A provisional diagnosis of multiple sclerosis was made. Her condition improved after the commencement of methylprednisolone.
Keywords: covid-19; demyelinating diseases; multiple sclerosis; post-covid complications; sars-cov-2.