tetano
Editor, Senior Moderator
Cureus
. 2021 Dec 4;13(12):e20158.
doi: 10.7759/cureus.20158. eCollection 2021 Dec.
Persistent Hiccups As Presenting Symptom of COVID-19: A Case of 64-Year-Old Male From International Medical Center, Jeddah, Saudi Arabia
Mohammed I Habadi[SUP] 1 [/SUP], Nashaat Hamza[SUP] 2 [/SUP], Tarig H Balla Abdalla[SUP] 3 [/SUP], Afnan Al-Gedeei[SUP] 4 [/SUP]
Affiliations
Abstract
The possibilities of coronavirus disease 2019 (COVID-19) to present with atypical manifestations have reported. Information of COVID-19 atypical signs and symptoms is still emerging globally. One of these presentations is persistent hiccups. One of the hypotheses is that COVID-19 has been linked to several neurological manifestations and effects. Some observations noticed phrenic nerve paralysis after COVID-19 infection leading to pulmonary failure. We report one case of COVID-19-positive patient where he presented with persistent hiccups. Many predisposing factors might lead to the development of hiccups in COVID-19 infection such as a history of smoking, phrenic and vagus nerve damage or irritation, high inflammatory markers, lower lobe pneumonia, ground-glass-like appearance on x-rays. We hypothesize that hiccups are the first sign of serious deterioration of patients with COVID-19 and such patients are at high risk of developing kidney injury and intubation.
Keywords: covid-19 hicupps; covid-19 presentation; hiccups; intractable hiccups; persistent hiccups.
. 2021 Dec 4;13(12):e20158.
doi: 10.7759/cureus.20158. eCollection 2021 Dec.
Persistent Hiccups As Presenting Symptom of COVID-19: A Case of 64-Year-Old Male From International Medical Center, Jeddah, Saudi Arabia
Mohammed I Habadi[SUP] 1 [/SUP], Nashaat Hamza[SUP] 2 [/SUP], Tarig H Balla Abdalla[SUP] 3 [/SUP], Afnan Al-Gedeei[SUP] 4 [/SUP]
Affiliations
- PMID: 35003987
- PMCID: PMC8723778
- DOI: 10.7759/cureus.20158
Abstract
The possibilities of coronavirus disease 2019 (COVID-19) to present with atypical manifestations have reported. Information of COVID-19 atypical signs and symptoms is still emerging globally. One of these presentations is persistent hiccups. One of the hypotheses is that COVID-19 has been linked to several neurological manifestations and effects. Some observations noticed phrenic nerve paralysis after COVID-19 infection leading to pulmonary failure. We report one case of COVID-19-positive patient where he presented with persistent hiccups. Many predisposing factors might lead to the development of hiccups in COVID-19 infection such as a history of smoking, phrenic and vagus nerve damage or irritation, high inflammatory markers, lower lobe pneumonia, ground-glass-like appearance on x-rays. We hypothesize that hiccups are the first sign of serious deterioration of patients with COVID-19 and such patients are at high risk of developing kidney injury and intubation.
Keywords: covid-19 hicupps; covid-19 presentation; hiccups; intractable hiccups; persistent hiccups.