tetano
Editor, Senior Moderator
Cureus
. 2022 Jan 13;14(1):e21203.
doi: 10.7759/cureus.21203. eCollection 2022 Jan.
When Worlds Collide: An Interesting Case of Rhinocerebral Mucormycosis Exacerbated by COVID-19 and Diabetic Ketoacidosis Complicated by Intraorbital Hematoma
Andrew J Ortega[SUP] 1 [/SUP], Sara Alhariri[SUP] 1 [/SUP], M Ammar Kalas[SUP] 1 [/SUP], Jeff Taclob[SUP] 1 [/SUP], Angelica Padilla[SUP] 2 [/SUP], Abhizith Deoker[SUP] 1 [/SUP]
Affiliations
Abstract
Mucormycosis is a devastating fungal infection seen in patients who are immunosuppressed or in severe inflammatory states. Mucormycosis has been increasingly seen in the setting of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. We describe a 68-year-old male with a past medical history of uncontrolled diabetes mellitus who presented with acute vision loss and was found to have concomitant diabetic ketoacidosis (DKA) and coronavirus disease 2019 (COVID-19) infection on presentation. Rhinocerebral mucormycosis was suspected given the patient's presentation and was confirmed with an ethmoidal sinus biopsy. Our case was further complicated by the presence of cavernous sinus thrombosis, cerebral infarcts, and, later, the development of a left orbital hematoma following therapeutic anticoagulation. This case report aims to address the rare but now increasing incidence of rhinocerebral mucormycosis in the setting of COVID-19, further complicated by DKA, cerebral thrombosis, and intraorbital hematoma.
Keywords: covid 19; covid-19 associated mucormycosis; diabetes type 2; diabetic ketoacidosis (dka); intra-orbital hematoma; rhinocerebral mucormycosis.
. 2022 Jan 13;14(1):e21203.
doi: 10.7759/cureus.21203. eCollection 2022 Jan.
When Worlds Collide: An Interesting Case of Rhinocerebral Mucormycosis Exacerbated by COVID-19 and Diabetic Ketoacidosis Complicated by Intraorbital Hematoma
Andrew J Ortega[SUP] 1 [/SUP], Sara Alhariri[SUP] 1 [/SUP], M Ammar Kalas[SUP] 1 [/SUP], Jeff Taclob[SUP] 1 [/SUP], Angelica Padilla[SUP] 2 [/SUP], Abhizith Deoker[SUP] 1 [/SUP]
Affiliations
- PMID: 35186519
- PMCID: PMC8844255
- DOI: 10.7759/cureus.21203
Abstract
Mucormycosis is a devastating fungal infection seen in patients who are immunosuppressed or in severe inflammatory states. Mucormycosis has been increasingly seen in the setting of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. We describe a 68-year-old male with a past medical history of uncontrolled diabetes mellitus who presented with acute vision loss and was found to have concomitant diabetic ketoacidosis (DKA) and coronavirus disease 2019 (COVID-19) infection on presentation. Rhinocerebral mucormycosis was suspected given the patient's presentation and was confirmed with an ethmoidal sinus biopsy. Our case was further complicated by the presence of cavernous sinus thrombosis, cerebral infarcts, and, later, the development of a left orbital hematoma following therapeutic anticoagulation. This case report aims to address the rare but now increasing incidence of rhinocerebral mucormycosis in the setting of COVID-19, further complicated by DKA, cerebral thrombosis, and intraorbital hematoma.
Keywords: covid 19; covid-19 associated mucormycosis; diabetes type 2; diabetic ketoacidosis (dka); intra-orbital hematoma; rhinocerebral mucormycosis.