tetano
Editor, Senior Moderator
Respirol Case Rep. 2017 Dec 22;6(2):e00291. doi: 10.1002/rcr2.291. eCollection 2018 Feb.
[h=1]Desquamative interstitial pneumonia complicated by diffuse alveolar haemorrhage.[/h] Matsuo A[SUP]1[/SUP], Matsumoto N[SUP]1[/SUP], Kitamura A[SUP]1[/SUP], Tsubouchi H[SUP]1[/SUP], Yanagi S[SUP]1[/SUP], Nakazato M[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] We report a rare case of desquamative interstitial pneumonia (DIP) with diffuse alveolar haemorrhage (DAH). A 56-year-old man diagnosed with DIP by surgical lung biopsy 2 years ago was admitted to our hospital because of severe acute respiratory failure. The DIP had progressed despite smoking cessation. On admission, the patient appeared extremely ill, and physical examination revealed respiratory distress. The patient required mechanical ventilation. High-resolution computed tomography showed diffuse ground glass opacity in both lungs. The bronchoalveolar lavage fluid was bloody, and numerous haemosiderin-laden alveolar macrophages were detected. Pulse steroid therapy followed by oral prednisolone immediately relieved the respiratory failure and improved the long-term control of the DIP. Paired sera tests confirmed the diagnosis of influenza A/H3N2 virus infection, which was the cause of the DAH. Chronically progressive DIP with acute respiratory failure due to DAH was successfully treated by steroid therapy.
[h=4]KEYWORDS:[/h] Desquamative interstitial pneumonia; diffuse alveolar haemorrhage; respiratory failure; steroid therapy
PMID: 29321935 PMCID: PMC5756715 DOI: 10.1002/rcr2.291
Free PMC Article
[h=1]Desquamative interstitial pneumonia complicated by diffuse alveolar haemorrhage.[/h] Matsuo A[SUP]1[/SUP], Matsumoto N[SUP]1[/SUP], Kitamura A[SUP]1[/SUP], Tsubouchi H[SUP]1[/SUP], Yanagi S[SUP]1[/SUP], Nakazato M[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] We report a rare case of desquamative interstitial pneumonia (DIP) with diffuse alveolar haemorrhage (DAH). A 56-year-old man diagnosed with DIP by surgical lung biopsy 2 years ago was admitted to our hospital because of severe acute respiratory failure. The DIP had progressed despite smoking cessation. On admission, the patient appeared extremely ill, and physical examination revealed respiratory distress. The patient required mechanical ventilation. High-resolution computed tomography showed diffuse ground glass opacity in both lungs. The bronchoalveolar lavage fluid was bloody, and numerous haemosiderin-laden alveolar macrophages were detected. Pulse steroid therapy followed by oral prednisolone immediately relieved the respiratory failure and improved the long-term control of the DIP. Paired sera tests confirmed the diagnosis of influenza A/H3N2 virus infection, which was the cause of the DAH. Chronically progressive DIP with acute respiratory failure due to DAH was successfully treated by steroid therapy.
[h=4]KEYWORDS:[/h] Desquamative interstitial pneumonia; diffuse alveolar haemorrhage; respiratory failure; steroid therapy
PMID: 29321935 PMCID: PMC5756715 DOI: 10.1002/rcr2.291
Free PMC Article