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Detection of Viruses and Mycoplasma pneumoniae in Hospitalized Patients with Severe Acute Respiratory Infection in Northern China, 2015-2016

tetano

Editor, Senior Moderator
Jpn J Infect Dis. 2018 Feb 28. doi: 10.7883/yoken.JJID.2017.412. [Epub ahead of print]
[h=1]Detection of Viruses and Mycoplasma pneumoniae in Hospitalized Patients with Severe Acute Respiratory Infection in Northern China, 2015-2016.[/h] Xu W[SUP]1[/SUP], Guo L[SUP]2[/SUP], Dong X[SUP]1[/SUP], Li X[SUP]3[/SUP], Zhou P[SUP]1[/SUP], Ni Q[SUP]3[/SUP], Zhou X[SUP]4[/SUP], Wagner AL[SUP]5[/SUP], Li L[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Severe acute respiratory infection (SARI) occupies a huge disease and economic burden in the world. The aim of this study was to describe the frequency and types of different infectious etiologies among hospitalized patients with SARI in Tianjin, China, from 2015-2016. SARI patients' basic information was collected, along with a throat or serum sample. Nine viruses were detected by RT-PCR, and Mycoplasma pneumoniae was detected by the serodia Myco II gelatin particle agglutination test. 585 specimens from 2290 SARI cases were collected. The most common infection (19.66%, 115/585) was M. pneumoniae, followed by influenza virus A/B (6.15%,36/585), RSV (4.96%,29/585). Identification of viral or M. pneumoniae infections was highest in the pediatric medicine ward (74.84%,119/159), compared with the intensive care units (37.04%,80/216) and the respiratory medicine ward (34.29%,72/210). M. pneumoniae was highest (38.71%,24/62) in the 5-14 year age group. Influenza was the main infection in January 2015 and March 2016. The correlation coefficient for the proportion of hospitalized cases with SARI and the positive detection rate within the same week was 0.25. M. pneumoniae and influenza were the leading pathogens among hospitalized SARI patients. Continued surveillance of hospitalized cases of SARI can detect emerging diseases such as avian influenza A (H7N9) virus and other respiratory disease outbreaks.


[h=4]KEYWORDS:[/h] Hospitalized patients; Mycoplasma pneumoniae; Respiratory viruses; Severe Acute Respiratory infection

PMID: 29491245 DOI: 10.7883/yoken.JJID.2017.412
 
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