tetano
Editor, Senior Moderator
Diabetes Ther
. 2023 Sep 26.
doi: 10.1007/s13300-023-01465-7. Online ahead of print. New-Onset Diabetes Mellitus in COVID-19: A Scoping Review
Anca Pantea Stoian[SUP] 1 2 [/SUP], Ioana-Cristina Bica[SUP] 3 [/SUP], Teodor Salmen[SUP] 2 [/SUP], Wael Al Mahmeed[SUP] 4 [/SUP], Khalid Al-Rasadi[SUP] 5 [/SUP], Kamila Al-Alawi[SUP] 6 [/SUP], Maciej Banach[SUP] 7 8 9 [/SUP], Yajnavalka Banerjee[SUP] 10 [/SUP], Antonio Ceriello[SUP] 11 [/SUP], Mustafa Cesur[SUP] 12 [/SUP], Francesco Cosentino[SUP] 13 [/SUP], Alberto Firenze[SUP] 14 [/SUP], Massimo Galia[SUP] 15 [/SUP], Su-Yen Goh[SUP] 16 [/SUP], Andrej Janez[SUP] 17 [/SUP], Sanjay Kalra[SUP] 18 [/SUP], Nitin Kapoor[SUP] 19 20 [/SUP], Peter Kempler[SUP] 21 [/SUP], Nader Lessan[SUP] 22 [/SUP], Paulo Lotufo[SUP] 23 [/SUP], Dimitri P Mikhaildiis[SUP] 10 24 [/SUP], Luigi Nibali[SUP] 25 [/SUP], Nikolaos Papanas[SUP] 26 [/SUP], Tiffany Powell-Wiley[SUP] 27 [/SUP], Ali A Rizvi[SUP] 28 [/SUP], Amirhossein Sahebkar[SUP] 29 30 31 [/SUP], Raul D Santos[SUP] 32 33 [/SUP], Peter P Toth[SUP] 33 34 [/SUP], Vijay Viswanathan[SUP] 35 [/SUP], Manfredi Rizzo[SUP] 1 10 36 [/SUP]; Cardiometabolic Panel of International Experts on Syndemic COVID-19 (CAPISCO)
Affiliations
Introduction: The coronavirus disease 2019 (COVID-19) pandemic became superimposed on the pre-existing obesity and diabetes mellitus (DM) pandemics. Since COVID-19 infection alters the metabolic equilibrium, it may induce pathophysiologic mechanisms that potentiate new-onset DM, and we evaluated this issue.
Method: A systematic review of the literature published from the 1 January 2020 until the 20 July 2023 was performed (PROSPERO registration number CRD42022341638). We included only full-text articles of both human clinical and randomized controlled trials published in English and enrolling adults (age > 18 years old) with ongoing or preceding COVID-19 in whom hyperglycemia was detected. The search was based on the following criteria: "(new-onset diabetes mellitus OR new-onset DM) AND (COVID-19) AND adults".
Results: Articles on MEDLINE (n = 70) and the Web of Science database (n = 16) were included and analyzed by two researchers who selected 20 relevant articles. We found evidence of a bidirectional relationship between COVID-19 and DM.
Conclusions: This link operates as a pathophysiological mechanism supported by epidemiological data and also by the clinical and biological findings obtained from the affected individuals. The COVID-19 pandemic raised the incidence of DM through different pathophysiological and psychosocial factors.
Keywords: Coronavirus disease 2019; Diabetes mellitus; Hyperglycemia; New-onset diabetes; New-onset hyperglycemia; Newly diagnosed diabetes; Prediabetes; Severe acute respiratory syndrome coronavirus-2 infection.
. 2023 Sep 26.
doi: 10.1007/s13300-023-01465-7. Online ahead of print. New-Onset Diabetes Mellitus in COVID-19: A Scoping Review
Anca Pantea Stoian[SUP] 1 2 [/SUP], Ioana-Cristina Bica[SUP] 3 [/SUP], Teodor Salmen[SUP] 2 [/SUP], Wael Al Mahmeed[SUP] 4 [/SUP], Khalid Al-Rasadi[SUP] 5 [/SUP], Kamila Al-Alawi[SUP] 6 [/SUP], Maciej Banach[SUP] 7 8 9 [/SUP], Yajnavalka Banerjee[SUP] 10 [/SUP], Antonio Ceriello[SUP] 11 [/SUP], Mustafa Cesur[SUP] 12 [/SUP], Francesco Cosentino[SUP] 13 [/SUP], Alberto Firenze[SUP] 14 [/SUP], Massimo Galia[SUP] 15 [/SUP], Su-Yen Goh[SUP] 16 [/SUP], Andrej Janez[SUP] 17 [/SUP], Sanjay Kalra[SUP] 18 [/SUP], Nitin Kapoor[SUP] 19 20 [/SUP], Peter Kempler[SUP] 21 [/SUP], Nader Lessan[SUP] 22 [/SUP], Paulo Lotufo[SUP] 23 [/SUP], Dimitri P Mikhaildiis[SUP] 10 24 [/SUP], Luigi Nibali[SUP] 25 [/SUP], Nikolaos Papanas[SUP] 26 [/SUP], Tiffany Powell-Wiley[SUP] 27 [/SUP], Ali A Rizvi[SUP] 28 [/SUP], Amirhossein Sahebkar[SUP] 29 30 31 [/SUP], Raul D Santos[SUP] 32 33 [/SUP], Peter P Toth[SUP] 33 34 [/SUP], Vijay Viswanathan[SUP] 35 [/SUP], Manfredi Rizzo[SUP] 1 10 36 [/SUP]; Cardiometabolic Panel of International Experts on Syndemic COVID-19 (CAPISCO)
Affiliations
- PMID: 37751143
- DOI: 10.1007/s13300-023-01465-7
Introduction: The coronavirus disease 2019 (COVID-19) pandemic became superimposed on the pre-existing obesity and diabetes mellitus (DM) pandemics. Since COVID-19 infection alters the metabolic equilibrium, it may induce pathophysiologic mechanisms that potentiate new-onset DM, and we evaluated this issue.
Method: A systematic review of the literature published from the 1 January 2020 until the 20 July 2023 was performed (PROSPERO registration number CRD42022341638). We included only full-text articles of both human clinical and randomized controlled trials published in English and enrolling adults (age > 18 years old) with ongoing or preceding COVID-19 in whom hyperglycemia was detected. The search was based on the following criteria: "(new-onset diabetes mellitus OR new-onset DM) AND (COVID-19) AND adults".
Results: Articles on MEDLINE (n = 70) and the Web of Science database (n = 16) were included and analyzed by two researchers who selected 20 relevant articles. We found evidence of a bidirectional relationship between COVID-19 and DM.
Conclusions: This link operates as a pathophysiological mechanism supported by epidemiological data and also by the clinical and biological findings obtained from the affected individuals. The COVID-19 pandemic raised the incidence of DM through different pathophysiological and psychosocial factors.
Keywords: Coronavirus disease 2019; Diabetes mellitus; Hyperglycemia; New-onset diabetes; New-onset hyperglycemia; Newly diagnosed diabetes; Prediabetes; Severe acute respiratory syndrome coronavirus-2 infection.