tetano
Editor, Senior Moderator
Virology. 2017 Feb 18;505:33-41. doi: 10.1016/j.virol.2017.02.009. [Epub ahead of print]
[h=1]Diversity, evolution and population dynamics of avian influenza viruses circulating in the live poultry markets in China.[/h] Chen LJ[SUP]1[/SUP], Lin XD[SUP]2[/SUP], Tian JH[SUP]3[/SUP], Liao Y[SUP]4[/SUP], Ying XH[SUP]5[/SUP], Shao JW[SUP]6[/SUP], Yu B[SUP]3[/SUP], Guo JJ[SUP]1[/SUP], Wang MR[SUP]7[/SUP], Peng Y[SUP]3[/SUP], Shi M[SUP]8[/SUP], Holmes EC[SUP]8[/SUP], Yang ZQ[SUP]9[/SUP], Zhang YZ[SUP]10[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Live poultry markets (LPMs) are an important source of novel avian influenza viruses (AIV). During 2015-2016 we surveyed AIV diversity in ten LPMs in Hubei, Zhejiang and Jiangxi provinces, China. A high diversity and prevalence of AIVs (totaling 12 subtypes) was observed in LPMs in these provinces. Strikingly, however, the subtypes discovered during 2015-2016 were markedly different to those reported by us in these same localities one year previously, suggesting a dynamic shift in viral genetic diversity over the course of a single year. Phylogenetic analyses revealed frequent reassortment, including between high and low pathogenic AIV subtypes and among those that circulate in domestic and wild birds. Notably, the novel H5N6 reassortant virus, which contains a set of H9N2-like internal genes, was prevalent in all three regions surveyed. Overall, these data highlight the profound changes in genetic diversity and in patterns of reassortment in those AIVs that circulate in LPMs.
Copyright ? 2017 Elsevier Inc. All rights reserved.
[h=4]KEYWORDS:[/h] Avian influenza virus; Evolution; H5N6 virus; Live poultry markets; Reassortant
PMID: 28222327 DOI: 10.1016/j.virol.2017.02.009
[PubMed - as supplied by publisher]
[h=1]Diversity, evolution and population dynamics of avian influenza viruses circulating in the live poultry markets in China.[/h] Chen LJ[SUP]1[/SUP], Lin XD[SUP]2[/SUP], Tian JH[SUP]3[/SUP], Liao Y[SUP]4[/SUP], Ying XH[SUP]5[/SUP], Shao JW[SUP]6[/SUP], Yu B[SUP]3[/SUP], Guo JJ[SUP]1[/SUP], Wang MR[SUP]7[/SUP], Peng Y[SUP]3[/SUP], Shi M[SUP]8[/SUP], Holmes EC[SUP]8[/SUP], Yang ZQ[SUP]9[/SUP], Zhang YZ[SUP]10[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Live poultry markets (LPMs) are an important source of novel avian influenza viruses (AIV). During 2015-2016 we surveyed AIV diversity in ten LPMs in Hubei, Zhejiang and Jiangxi provinces, China. A high diversity and prevalence of AIVs (totaling 12 subtypes) was observed in LPMs in these provinces. Strikingly, however, the subtypes discovered during 2015-2016 were markedly different to those reported by us in these same localities one year previously, suggesting a dynamic shift in viral genetic diversity over the course of a single year. Phylogenetic analyses revealed frequent reassortment, including between high and low pathogenic AIV subtypes and among those that circulate in domestic and wild birds. Notably, the novel H5N6 reassortant virus, which contains a set of H9N2-like internal genes, was prevalent in all three regions surveyed. Overall, these data highlight the profound changes in genetic diversity and in patterns of reassortment in those AIVs that circulate in LPMs.
Copyright ? 2017 Elsevier Inc. All rights reserved.
[h=4]KEYWORDS:[/h] Avian influenza virus; Evolution; H5N6 virus; Live poultry markets; Reassortant
PMID: 28222327 DOI: 10.1016/j.virol.2017.02.009
[PubMed - as supplied by publisher]