tetano
Editor, Senior Moderator
Echocardiography
. 2021 Jul 19.
doi: 10.1111/echo.15160. Online ahead of print.
Cardiac involvement in MRI in young population after COVID-19: A single tertiary center experience
Mehmet Akif Erdol[SUP] 1 [/SUP], Mustafa Bilal Ozbay[SUP] 2 [/SUP], Cagri Yayla[SUP] 1 [/SUP], Halil Arslan[SUP] 3 [/SUP], Nilgün Isiksalan Ozbulbul[SUP] 4 [/SUP], Elif Hande Ozcan Cetin[SUP] 1 [/SUP], Mustafa Karanfil[SUP] 1 [/SUP], Mehmet Erdoğan[SUP] 5 [/SUP], Koray Demirtas[SUP] 1 [/SUP], Ahmet Göktuğ Ertem[SUP] 1 [/SUP], Adnan Burak Akcay[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Coronavirus 2019 (COVID-19) causes morbidity and mortality in an increasing number of people worldwide. Although it mainly affects the respiratory system, it influences all organs, including the heart. It is associated with a broad spectrum of widespread cardiovascular problems ranging from mild myocardial injury to fulminant myocarditis. We aimed to evaluate the presence and prevalence of cardiac involvement in asymptomatic or symptomatic patients after they recovered from COVID 19 infection.
Methods: A total of 100 consecutive patients with COVID-19 proven by reverse transcription polymerase chain reaction (RT-PCR), under 40 years of age and without any known additional chronic diseases were analyzed retrospectively for cardiac magnetic resonance (CMR) results and symptoms.
Results: Cardiac involvement was detected in 49 out of 100 patients on CMR imaging. In the cardiac involvement group, the number of patients with chest pain and/or dyspnea was 41 (84%), which was statistically significant (p = 0.001). Twenty-four patients (47%) in the without cardiac involvement group were asymptomatic and this was also statistically significant (p = 0.001). LV ejection fraction was statistically significantly lower in the group with cardiac involvement (61% vs 66%, p = 0.001). LV stroke volume and tricuspid annular plane systolic excursion (TAPSE) were statistically significantly lower in patients with cardiac involvement (p = 0.028 and p = 0.019, respectively).
Conclusion: Based on single center experience, myocardial involvement is common in symptomatic patients after COVID-19. More studies are needed for long-term side effects and clinical results in these patients.
Keywords: COVID-19; cardiac MR; cardiac involvement; chest pain; dyspnea; myocarditis.
. 2021 Jul 19.
doi: 10.1111/echo.15160. Online ahead of print.
Cardiac involvement in MRI in young population after COVID-19: A single tertiary center experience
Mehmet Akif Erdol[SUP] 1 [/SUP], Mustafa Bilal Ozbay[SUP] 2 [/SUP], Cagri Yayla[SUP] 1 [/SUP], Halil Arslan[SUP] 3 [/SUP], Nilgün Isiksalan Ozbulbul[SUP] 4 [/SUP], Elif Hande Ozcan Cetin[SUP] 1 [/SUP], Mustafa Karanfil[SUP] 1 [/SUP], Mehmet Erdoğan[SUP] 5 [/SUP], Koray Demirtas[SUP] 1 [/SUP], Ahmet Göktuğ Ertem[SUP] 1 [/SUP], Adnan Burak Akcay[SUP] 1 [/SUP]
Affiliations
- PMID: 34286876
- DOI: 10.1111/echo.15160
Abstract
Background: Coronavirus 2019 (COVID-19) causes morbidity and mortality in an increasing number of people worldwide. Although it mainly affects the respiratory system, it influences all organs, including the heart. It is associated with a broad spectrum of widespread cardiovascular problems ranging from mild myocardial injury to fulminant myocarditis. We aimed to evaluate the presence and prevalence of cardiac involvement in asymptomatic or symptomatic patients after they recovered from COVID 19 infection.
Methods: A total of 100 consecutive patients with COVID-19 proven by reverse transcription polymerase chain reaction (RT-PCR), under 40 years of age and without any known additional chronic diseases were analyzed retrospectively for cardiac magnetic resonance (CMR) results and symptoms.
Results: Cardiac involvement was detected in 49 out of 100 patients on CMR imaging. In the cardiac involvement group, the number of patients with chest pain and/or dyspnea was 41 (84%), which was statistically significant (p = 0.001). Twenty-four patients (47%) in the without cardiac involvement group were asymptomatic and this was also statistically significant (p = 0.001). LV ejection fraction was statistically significantly lower in the group with cardiac involvement (61% vs 66%, p = 0.001). LV stroke volume and tricuspid annular plane systolic excursion (TAPSE) were statistically significantly lower in patients with cardiac involvement (p = 0.028 and p = 0.019, respectively).
Conclusion: Based on single center experience, myocardial involvement is common in symptomatic patients after COVID-19. More studies are needed for long-term side effects and clinical results in these patients.
Keywords: COVID-19; cardiac MR; cardiac involvement; chest pain; dyspnea; myocarditis.