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Economic Cost of Severe Acute Respiratory Infection Associated to Influenza in Colombian Children: A Single Setting Analysis

tetano

Editor, Senior Moderator
Value Health Reg Issues. 2019 Sep 26;20:159-163. doi: 10.1016/j.vhri.2019.07.010. [Epub ahead of print] [h=1]Economic Cost of Severe Acute Respiratory Infection Associated to Influenza in Colombian Children: A Single Setting Analysis.[/h]
Salcedo-Mej?a F[SUP]1[/SUP], Alvis-Zakzuk NJ[SUP]2[/SUP], Carrasquilla-Sotomayor M[SUP]3[/SUP], Redondo HP[SUP]4[/SUP], Casta?eda-Orjuela C[SUP]5[/SUP], De la Hoz-Restrepo F[SUP]6[/SUP], Alvis-Guzm?n N[SUP]7[/SUP].
[h=3]Author information[/h] 1 Departamento de An?lisis de Datos, ALZAK Foundation, Cartagena, Colombia. 2 Departamento de Ciencias Empresariales, Universidad de la Costa-CUC, Barranquilla, Colombia; Observatorio Nacional de Salud, Instituto Nacional de Salud, Bogot?, DC, Colombia. Electronic address: alviszakzuk@gmail.com. 3 Departamento de Evaluaciones Econ?micas, ALZAK Foundation, Cartagena, Colombia. 4 Grupo de Investigaci?n de Infectolog?a Peditrica, Fundaci?n Hospital Infantil Napole?n Franco Pareja, Universidad de Cartagena, Cartagena, Colombia. 5 Observatorio Nacional de Salud, Instituto Nacional de Salud, Bogot?, DC, Colombia; Grupo de Evaluaci?n en Epidemiolog?a y Salud P?blica, Universidad Nacional de Colombia, Bogot?, DC, Colombia. 6 Grupo de Evaluaci?n en Epidemiolog?a y Salud P?blica, Universidad Nacional de Colombia, Bogot?, DC, Colombia. 7 Departamento de Ciencias Empresariales, Universidad de la Costa-CUC, Barranquilla, Colombia; Departamento de Econom?a, Universidad de Cartagena, Cartagena, Colombia.

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Influenza is considered a leading public health problem because its large economic burden of disease worldwide, especially in low-and middle-income countries, such as Colombia.
[h=4]OBJECTIVE:[/h] We aimed to estimate the economic costs of influenza-confirmed patients in a pediatric hospital in Cartagena, Colombia.
[h=4]METHODS:[/h] We conducted a retrospective costing analysis. We estimated the direct (direct medical and out-of-pocket expenditures) and indirect costs for influenza-confirmed severe acute respiratory infection cases from a societal perspective. Total economic costs were calculated adding direct medical costs, out-of-pocket expenditures, and indirect costs owing to loss of productivity of caregivers. Mean, median, 95% confidence interval (95% CI) and interquartile range (IQR) of costs were measured. All costs are reported in USD ($1.00 = COP$2000.7) RESULTS: Forty-four cases were included in the analysis: 30 had influenza B, 10 influenza A and B, and 4 influenza AH1N1. Thirty patients were hospitalized in the general ward, 14 went to the intensive care unit. The average duration of stay was ∼9 days (95% CI, 6.3-11.5). The median direct medical cost for hospitalized case in general ward was $743.50 (IQR $590.20-$1404.60) and in intensive care unit $4669.80 (IQR $1614.60-$7801.50). The economic cost per hospitalized case was $1826.10 (IQR $1343.30-$2376.50); direct medical costs represented 93.8% of this cost. The median indirect cost was $82.10 (IQR $41.10-$133.40) and the median out-of-pocket expenditure per case was $45.70 (IQR $29.50-$64.90).
[h=4]CONCLUSIONS:[/h] Severe acute respiratory infection is an important source of economic burden for the health system, families, and society in Colombia. Seasonal influenza vaccination should be strengthened to prevent more cases and save economic resources.
Copyright ? 2019 ISPOR--The professional society for health economics and outcomes research. Published by Elsevier Inc. All rights reserved.


[h=4]KEYWORDS:[/h] acute respiratory infection; cost analysis; direct cost; indirect cost; out-of-pocket

PMID: 31563859 DOI: 10.1016/j.vhri.2019.07.010
 
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