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Effect of risk factors on the prevalence of influenza infections among children of slums of Dhaka city

tetano

Editor, Senior Moderator
Springerplus. 2016 May 11;5:602. doi: 10.1186/s40064-016-2275-5. eCollection 2016.
[h=1]Effect of risk factors on the prevalence of influenza infections among children of slums of Dhaka city.[/h] Rahman SR[SUP]1[/SUP], Ahmed MF[SUP]2[/SUP], Islam MA[SUP]3[/SUP], Majibur Rahman M[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Influenza viruses may cause severe acute respiratory illness among human population. People of densely populated areas, e.g., slum, are mostly affected by influenza viruses. Although potential vaccines to influenza viruses have been developed, infection rate is still high, therefore, increase the morbidity and mortality rate in slum areas. To treat these infections, slum dwellers including children and mothers do not get proper medication as well as vaccination. Hence, prevention remains to be the only mean to tackle such infections. Herein, we determined the prevalence of influenza infections among nutritionally deprived children and mothers of slum areas in Dhaka city and demonstrated the association with different risk factors like age, gender and socio-economic status.
[h=4]RESULTS:[/h] Nasopharyngeal swab samples and a short demography of all the participants suffering from influenza-like illness (ILI) were collected. The samples were subjected to RNA extraction and then real-time RT-PCR to detect influenza viruses. Among the ILI patients, about 87.9 % did not have knowledge about influenza infections and 80.5 % did not cover their noses during coughing as well as sneezing. Children were significantly infected by both influenza A and influenza B viruses, suggesting their vulnerability to these infections. Additionally, among the children with ILI, influenza infections were significantly associated with age below or equal to three years, very poor family incomes, practicing unhygienic habits and nutritional deficiency.
[h=4]CONCLUSIONS:[/h] This study suggests that proper vaccination, improved sanitary conditions and nutritional diet may help reduce the risk of influenza infections in slum areas.


[h=4]KEYWORDS:[/h] Children; Influenza; Nutrition; RT-PCR; Risk factors

PMID: 27247898 [PubMed] PMCID: PMC4864765 Free PMC Article
 
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