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EID: Reassortant Highly Pathogenic Influenza A(H5N6) Virus in Laos

tetano

Editor, Senior Moderator
Frank Y.K. WongComments to Author , Phouvong Phommachanh, Wantanee Kalpravidh, Chintana Chanthavisouk, Jeffrey Gilbert, John Bingham, Kelly R. Davies, Julie Cooke, Debbie Eagles, Sithong Phiphakhavong, Songhua Shan, Vittoria Stevens, David T. Williams, Phachone Bounma, Bounkhouang Khambounheuang, Christopher Morrissy, Bounlom Douangngeun, and Subhash Morzaria
Author affiliations: Commonwealth Scientific and Industrial Research Organisation Australian Animal Health Laboratory, Geelong, Victoria, Australia (F.Y.K. Wong, J. Bingham, K.R. Davies, J. Cooke, D. Eagles, S. Shan, V. Stevens, D.T. Williams, C. Morrissy); National Animal Health Laboratory, Vientiane, Laos (P. Phommachanh, B. Douangngeun); Ministry of Agriculture and Forestry, Vientiane (S. Phiphakhavong, P. Bounma, B. Khambounheuang); Food and Agricultural Organization of the United Nations Regional Office for Asia and the Pacific, Bangkok, Thailand (W. Kalpravidh, C. Chanthavisouk, J. Gilbert, S. Morzaria)

Suggested citation for this article
Abstract

In March 2014, avian influenza in poultry in Laos was caused by an emergent influenza A(H5N6) virus. Genetic analysis indicated that the virus had originated from reassortment of influenza A(H5N1), clade 2.3.2.1b, variant clade 2.3.4, and influenza A(H6N6) viruses that circulate broadly in duck populations in southern and eastern China.

Asian lineage influenza A(H5N1) viruses continue to cause serious disease in poultry and sporadic human infections (1). This disease was reported in 2004 in poultry in Laos that were infected with clade 1 influenza A(H5N1) virus and subsequently in poultry infected with clade 2.3.4 and 2.3.2 viruses in 2006 and 2008, respectively (2,3). Interclade reassortant influenza A(H5N1) virus genotypes homologous to viruses circulating in southern China and Vietnam have also been detected, which indicated previous transboundary virus transfers. However, influenza A(H5N1) virus in poultry has not been reported in Laos since mid-2010 (4). We report highly pathogenic avian influenza (HPAI) in poultry in Laos in March 2014 that was caused by an emergent reassortant influenza A(H5N6) virus, apparently imported by live poultry from China.

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http://wwwnc.cdc.gov/eid/article/21/3/14-1488_article
 
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