tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2020 Aug 28;26(12).
doi: 10.3201/eid2612.203334. Online ahead of print.
Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020
William T Hu, J Christina Howell, Tugba Ozturk, Karima Benameur, Leda C Bassit, Richard Ramonell, Kevin S Cashman, Shama Pirmohammed, John D Roback, Vincent C Marconi, Irene Yang, Valerie V Mac, Daniel Smith, Ignasio Sanz, Whitney Wharton, F Eun-Hyung Lee, Raymond F Schinazi
Abstract
Among patients with coronavirus disease (COVID-19), IgM levels increased early after symptom onset for those with mild and severe disease, but IgG levels increased early only in those with severe disease. A similar pattern was observed in a separate serosurveillance cohort. Mild COVID-19 should be investigated separately from severe COVID-19.
Keywords: 2019 novel coronavirus disease; Atlanta; COVID-19; Georgia; SARS-CoV-2; USA; antibody profiles; coronavirus disease; immunoglobulin; infection severity; neutralization; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.
. 2020 Aug 28;26(12).
doi: 10.3201/eid2612.203334. Online ahead of print.
Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020
William T Hu, J Christina Howell, Tugba Ozturk, Karima Benameur, Leda C Bassit, Richard Ramonell, Kevin S Cashman, Shama Pirmohammed, John D Roback, Vincent C Marconi, Irene Yang, Valerie V Mac, Daniel Smith, Ignasio Sanz, Whitney Wharton, F Eun-Hyung Lee, Raymond F Schinazi
- PMID: 32857691
- DOI: 10.3201/eid2612.203334
Abstract
Among patients with coronavirus disease (COVID-19), IgM levels increased early after symptom onset for those with mild and severe disease, but IgG levels increased early only in those with severe disease. A similar pattern was observed in a separate serosurveillance cohort. Mild COVID-19 should be investigated separately from severe COVID-19.
Keywords: 2019 novel coronavirus disease; Atlanta; COVID-19; Georgia; SARS-CoV-2; USA; antibody profiles; coronavirus disease; immunoglobulin; infection severity; neutralization; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.