tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2021 Aug 5;27(10).
doi: 10.3201/eid2710.210538. Online ahead of print.
Bloodstream Infection Risk, Incidence, and Deaths for Hospitalized Patients during Coronavirus Disease Pandemic
Bhavarth S Shukla, Prem R Warde, Eric Knott, Sebastian Arenas, Darryl Pronty, Reinaldo Ramirez, Arely Rego, Miriam Levy, Martin Zak, Dipen J Parekh, Tanira Ferreira, Hayley B Gershengorn
Abstract
Hospital-acquired infections are emerging major concurrent conditions during the coronavirus disease (COVID-19) pandemic. We conducted a retrospective review of hospitalizations during March‒October 2020 of adults tested by reverse transcription PCR for severe acute respiratory syndrome coronavirus 2. We evaluated associations of COVID-19 diagnosis with risk for laboratory-confirmed bloodstream infections (LCBIs, primary outcome), time to LCBI, and risk for death by using logistic and competing risks regression with adjustment for relevant covariates. A total of 10,848 patients were included in the analysis: 918 (8.5%) were given a diagnosis of COVID-19, and 232 (2.1%) had LCBIs during their hospitalization. Of these patients, 58 (25%) were classified as having central line‒associated bloodstream infections. After adjusting for covariates, COVID-19‒positive status was associated with higher risk for LCBI and death. Reinforcement of infection control practices should be implemented in COVID-19 wards, and review of superiority and inferiority ranking methods by National Healthcare Safety Network criteria might be needed.
Keywords: COVID-19; SARS-CoV-2; bloodstream infection risk; coronavirus disease; coronaviruses; deaths; hospitalized patients; incidence; infection control; pandemic; prone positioning; respiratory infections; severe acute respiratory coronavirus 2; viruses; zoonoses.
. 2021 Aug 5;27(10).
doi: 10.3201/eid2710.210538. Online ahead of print.
Bloodstream Infection Risk, Incidence, and Deaths for Hospitalized Patients during Coronavirus Disease Pandemic
Bhavarth S Shukla, Prem R Warde, Eric Knott, Sebastian Arenas, Darryl Pronty, Reinaldo Ramirez, Arely Rego, Miriam Levy, Martin Zak, Dipen J Parekh, Tanira Ferreira, Hayley B Gershengorn
- PMID: 34352195
- DOI: 10.3201/eid2710.210538
Abstract
Hospital-acquired infections are emerging major concurrent conditions during the coronavirus disease (COVID-19) pandemic. We conducted a retrospective review of hospitalizations during March‒October 2020 of adults tested by reverse transcription PCR for severe acute respiratory syndrome coronavirus 2. We evaluated associations of COVID-19 diagnosis with risk for laboratory-confirmed bloodstream infections (LCBIs, primary outcome), time to LCBI, and risk for death by using logistic and competing risks regression with adjustment for relevant covariates. A total of 10,848 patients were included in the analysis: 918 (8.5%) were given a diagnosis of COVID-19, and 232 (2.1%) had LCBIs during their hospitalization. Of these patients, 58 (25%) were classified as having central line‒associated bloodstream infections. After adjusting for covariates, COVID-19‒positive status was associated with higher risk for LCBI and death. Reinforcement of infection control practices should be implemented in COVID-19 wards, and review of superiority and inferiority ranking methods by National Healthcare Safety Network criteria might be needed.
Keywords: COVID-19; SARS-CoV-2; bloodstream infection risk; coronavirus disease; coronaviruses; deaths; hospitalized patients; incidence; infection control; pandemic; prone positioning; respiratory infections; severe acute respiratory coronavirus 2; viruses; zoonoses.