tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2022 Feb 24;28(4).
doi: 10.3201/eid2804.212037. Online ahead of print.
Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers
Eric D Laing, Carol D Weiss, Emily C Samuels, Si'Ana A Coggins, Wei Wang, Richard Wang, Russell Vassell, Spencer L Sterling, Marana S Tso, Tonia Conner, Emilie Goguet, Matthew Moser, Belinda M Jackson-Thompson, Luca Illinik, Julian Davies, Orlando Ortega, Edward Parmelee, Monique Hollis-Perry, Santina E Maiolatesi, Gregory Wang, Kathleen F Ramsey, Anatalio E Reyes, Yolanda Alcorta, Mimi A Wong, Alyssa R Lindrose, Christopher A Duplessis, David R Tribble, Allison M W Malloy, Timothy H Burgess, Simon D Pollett, Cara H Olsen, Christopher C Broder, Edward Mitre
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 experienced outpatient symptomatic breakthrough infections, despite 59/227 exhibiting serologic evidence of SARS-CoV-2 infection, defined as presence of nucleocapsid protein antibodies.
Keywords: BNT162b2; COVID-19; SARS-CoV-2; United States; coronavirus disease; healthcare workers; respiratory infections; severe acute respiratory syndrome coronavirus 2; vaccine-preventable diseases; viruses; zoonoses.
. 2022 Feb 24;28(4).
doi: 10.3201/eid2804.212037. Online ahead of print.
Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers
Eric D Laing, Carol D Weiss, Emily C Samuels, Si'Ana A Coggins, Wei Wang, Richard Wang, Russell Vassell, Spencer L Sterling, Marana S Tso, Tonia Conner, Emilie Goguet, Matthew Moser, Belinda M Jackson-Thompson, Luca Illinik, Julian Davies, Orlando Ortega, Edward Parmelee, Monique Hollis-Perry, Santina E Maiolatesi, Gregory Wang, Kathleen F Ramsey, Anatalio E Reyes, Yolanda Alcorta, Mimi A Wong, Alyssa R Lindrose, Christopher A Duplessis, David R Tribble, Allison M W Malloy, Timothy H Burgess, Simon D Pollett, Cara H Olsen, Christopher C Broder, Edward Mitre
- PMID: 35203111
- DOI: 10.3201/eid2804.212037
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 experienced outpatient symptomatic breakthrough infections, despite 59/227 exhibiting serologic evidence of SARS-CoV-2 infection, defined as presence of nucleocapsid protein antibodies.
Keywords: BNT162b2; COVID-19; SARS-CoV-2; United States; coronavirus disease; healthcare workers; respiratory infections; severe acute respiratory syndrome coronavirus 2; vaccine-preventable diseases; viruses; zoonoses.
