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Emerg Infect Dis . Economic Evaluation of Wastewater Surveillance Combined with Clinical COVID-19 Screening Tests, Japan

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2023 Aug;29(8):1608-1617.
doi: 10.3201/eid2908.221775.
Economic Evaluation of Wastewater Surveillance Combined with Clinical COVID-19 Screening Tests, Japan

Byung-Kwang Yoo, Ryo Iwamoto, Ungil Chung, Tomoko Sasaki, Masaaki Kitajima
Abstract

The COVID-19 pandemic has imposed substantial burdens on the global society. To find an optimal combination of wastewater surveillance and clinical testing for tracking COVID-19, we evaluated the economic efficiency of hypothetical screening options at a single facility in Japan. To conduct cost-benefit analyses, we developed standard decision models in which we assumed model parameters from literature and primary data, such as screening policies used at the Tokyo Olympic and Paralympic Village in 2021. We compared hypothetical 2-step screening options that used clinical PCR to diagnose COVID-19 after a positive result from primary screening using antigen tests (option 1) or wastewater surveillance (option 2). Our simulation results indicated that option 2 likely would be economically more justifiable than option 1, particularly at lower incidence levels. Our findings could help justify and promote the use of wastewater surveillance as a primary screening at a facility level for COVID-19 and other infectious diseases.

Keywords: BCR; COVID-19; Japan; ROI; SARS; SARS-CoV-2; benefit to cost ratio; coronavirus; coronavirus disease; cost benefit analysis; economic efficiency; economic evaluation; respiratory infections; return on investment; screening; severe acute respiratory syndrome coronavirus 2; viruses; wastewater surveillance; zoonoses.
 
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