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Emerg Infect Dis. Effects of Vaccination against Pandemic (H1N1) 2009 among Japanese Children

Giuseppe

Emeritus
Effects of Vaccination against Pandemic (H1N1) 2009 among Japanese Children (Emerg Infect Dis., extract, edited)


[Source: US Centers for Disease Control and Prevention, Emerging Infectious Diseases Journal, full text: <cite cite="http://www.cdc.gov/eid/content/17/4/746.htm">Effects of Vaccination against Pandemic (H1N1) 2009 among Japanese Children | CDC EID</cite>. Extract, edites.]

Volume 17, Number 4?April 2011

Letter

Effects of Vaccination against Pandemic (H1N1) 2009 among Japanese Children

Hiroshi Nishiura and Hitoshi Oshitani

Author affiliations: Japan Science and Technology Agency, Saitama, Japan (H. Nishiura); University of Utrecht, Utrecht, the Netherlands (H. Nishiura); and Tohoku University Graduate School of Medicine, Sendai, Japan (H. Oshitani)


To the Editor:

We report findings from a household-based study on the protective effects of vaccination against pandemic (H1N1) 2009 among Japanese children. In Japan, prioritized vaccination started in October 2009, focusing on health care workers, pregnant women, persons with underlying diseases, and children 1?9 years of age. Only nonadjuvant split vaccines (inactivated) produced by 4 manufacturers (Denka Seiken, Tokyo, Japan; Kaketsuken, Kumamoto-shi, Japan; Kitasato, Tokyo, Japan; and Biken, Suita-shi, Japan) were used by the end of January 2010 (1). Because the protective effects of vaccination at the individual level are best measured by household data (2), we conducted a retrospective household survey involving 1,614 nonrandomly sampled households (i.e., based on area sampling of households across Japan, according to the regional population size, with a total of 6,356 household members), in which the earliest cases were diagnosed from October 2009 to mid-February 2010. Our study aimed to assess vaccine-induced reductions in susceptibility and infectiousness among children by using the household secondary attack rate.

(...)
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