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Emerg Infect Dis . Limited Protection of Inactivated SARS-CoV-2 Vaccine against Wuhan Strain and Variants of Concern

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2021 Sep 24;27(12).
doi: 10.3201/eid2712.211772. Online ahead of print.
Limited Protection of Inactivated SARS-CoV-2 Vaccine against Wuhan Strain and Variants of Concern

Taweewun Hunsawong, Stefan Fernandez, Rome Buathong, Naretrit Khadthasrima, Kamonthip Rungrojchareonkit, Jindarat Lohachanakul, Rungarun Suthangkornkul, Kedsara Tayong, Angkana T Huang, Chonticha Klungthong, Piyawan Chinnawirotpisan, Yongyuth Poolpanichupatam, Anthony R Jones, Eric D Lombardini, Supaporn Wacharapluesadee, Opass Putcharoen

Abstract

In vitro determination of severe acute respiratory syndrome coronavirus 2 neutralizing antibodies induced in serum samples from recipients of the CoronaVac vaccine showed a short protection period against the original virus strain and limited protection against variants of concern. These data provide support for vaccine boosters, especially variants of concern circulate.

Keywords: COVID 19; SARS-CoV-2; Thailand; coronavirus disease; inactivated SARS-CoV-2 vaccine; neutralizing antibodies; respiratory infections; severe acute respiratory syndrome coronavirus 2; vaccination; viruses.
 
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