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Emerg Infect Dis . Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2021 Sep 14;27(11).
doi: 10.3201/eid2711.211174. Online ahead of print.
Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis [SUP]1[/SUP]

Nico A F Janssen, Rémy Nyga, Lore Vanderbeke, Cato Jacobs, Mehmet Ergün, Jochem B Buil, Karin van Dijk, Josje Altenburg, Catherine S C Bouman, Hans I van der Spoel, Bart J A Rijnders, Albert Dunbar, Jeroen A Schouten, Katrien Lagrou, Marc Bourgeois, Marijke Reynders, Niels van Regenmortel, Lynn Rutsaert, Piet Lormans, Simon Feys, Yves Debavaye, Fabienne Tamion, Damien Costa, Julien Maizel, Hervé Dupont, Taieb Chouaki, Saad Nseir, Boualem Sendid, Roger J M Brüggemann, Frank L van de Veerdonk, Joost Wauters, Paul E Verweij

Abstract

We performed an observational study to investigate intensive care unit incidence, risk factors, and outcomes of coronavirus disease-associated pulmonary aspergillosis (CAPA). We found 10%-15% CAPA incidence among 823 patients in 2 cohorts. Several factors were independently associated with CAPA in 1 cohort and mortality rates were 43%-52%.

Keywords: Aspergillus; COVID-19; SARS; SARS-CoV-2; coronavirus; coronavirus disease; epidemiology; fungi; invasive pulmonary aspergillosis; mortality rates; mycology; respiratory infections; risk factors; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.
 
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