tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2021 Aug 31;27(11).
doi: 10.3201/eid2711.211353. Online ahead of print.
Mutations Associated with SARS-CoV-2 Variants of Concern, Benin, Early 2021
Anna-Lena Sander, Anges Yadouleton, Edmilson F de Oliveira Filho, Carine Tchibozo, Gildas Hounkanrin, Yvette Badou, Praise Adewumi, Keke K René, Dossou Ange, Salifou Sourakatou, Eclou Sedjro, Melchior A J Aïssi, Hinson Fidelia, Mamoudou Harouna Djingarey, Michael Nagel, Wendy Karen, Andres Moreira-Soto, Christian Drosten, Olfert Landt, Victor Max Corman, Benjamin Hounkpatin, Jan Felix Drexler
Abstract
Intense transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa might promote emergence of variants. We describe 10 SARS-CoV-2 lineages in Benin during early 2021 that harbored mutations associated with variants of concern. Benin-derived SARS-CoV-2 strains were more efficiently neutralized by antibodies derived from vaccinees than patients, warranting accelerated vaccination in Africa.
Keywords: Benin; COVID-19; SARS-CoV-2; West Africa; coronavirus disease; mutations; respiratory infections; severe acute respiratory syndrome coronavirus 2; variant of concern; viruses; zoonoses.
. 2021 Aug 31;27(11).
doi: 10.3201/eid2711.211353. Online ahead of print.
Mutations Associated with SARS-CoV-2 Variants of Concern, Benin, Early 2021
Anna-Lena Sander, Anges Yadouleton, Edmilson F de Oliveira Filho, Carine Tchibozo, Gildas Hounkanrin, Yvette Badou, Praise Adewumi, Keke K René, Dossou Ange, Salifou Sourakatou, Eclou Sedjro, Melchior A J Aïssi, Hinson Fidelia, Mamoudou Harouna Djingarey, Michael Nagel, Wendy Karen, Andres Moreira-Soto, Christian Drosten, Olfert Landt, Victor Max Corman, Benjamin Hounkpatin, Jan Felix Drexler
- PMID: 34463240
- DOI: 10.3201/eid2711.211353
Abstract
Intense transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa might promote emergence of variants. We describe 10 SARS-CoV-2 lineages in Benin during early 2021 that harbored mutations associated with variants of concern. Benin-derived SARS-CoV-2 strains were more efficiently neutralized by antibodies derived from vaccinees than patients, warranting accelerated vaccination in Africa.
Keywords: Benin; COVID-19; SARS-CoV-2; West Africa; coronavirus disease; mutations; respiratory infections; severe acute respiratory syndrome coronavirus 2; variant of concern; viruses; zoonoses.