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Emerg Infect Dis . Pathogenesis and Transmissibility of North American Highly Pathogenic Avian Influenza A(H5N1) Virus in Ferrets

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2022 Jul 15;28(9).
doi: 10.3201/eid2809.220879. Online ahead of print.
Pathogenesis and Transmissibility of North American Highly Pathogenic Avian Influenza A(H5N1) Virus in Ferrets

Joanna A Pulit-Penaloza, Jessica A Belser, Nicole Brock, Poulami Basu Thakur, Terrence M Tumpey, Taronna R Maines
Free article

Abstract

Highly pathogenic avian influenza A(H5N1) viruses have spread rapidly throughout North American flyways in recent months, affecting wild birds in over 40 states. We evaluated the pathogenicity and transmissibility of a representative virus using a ferret model and examined replication kinetics of this virus in human respiratory tract cells.

Keywords: H5N1; avian influenza; cell culture; ferret; influenza; respiratory infections; transmission; vaccine-preventable diseases; viruses; zoonoses.
 
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