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Emerg Infect Dis . Population-Based Matched Cohort Study of COVID-19 Healthcare Costs, Ontario, Canada

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2025 Apr;31(4):710-719.
doi: 10.3201/eid3104.241463.
Population-Based Matched Cohort Study of COVID-19 Healthcare Costs, Ontario, Canada

Beate Sander, Sharmistha Mishra, Sarah Swayze, Yeva Sahakyan, Raquel Duchen, Kieran Quinn, Naveed Janjua, Hind Sbihi, Jeffrey Kwong
Free article Abstract

Estimates of COVID-19-related healthcare costs are key to health system planning, but attributable cost data remain limited. We characterized healthcare costs attributable to COVID-19 through a population-based matched cohort study in Ontario, Canada, by using health administrative data. We matched SARS-CoV-2-positive persons from 2020 to unexposed historical control persons from 2016-2018. We estimated phase-based and survival-adjusted COVID-19-attributable healthcare costs from the health system perspective. We matched 159,817 persons. Mean (95% CI) attributable 10-day costs per person were $1 ($-4 to $6) preindex, $240 ($231-$249) during acute care, $18 ($14-$21) in postacute phases, $3,928 ($3,471-$4,384) in the terminal phase for early deaths, and $1,781 ($1,182-$2,380) for late deaths. Mean cumulative survival-adjusted cost at 360 days was $2,553 ($2,348-$2,756) per person. SARS-CoV-2 infection is associated with substantial long-term healthcare costs, consistent with understanding of post-COVID condition. Determining phase-specific costs can inform budget and pandemic planning.

Keywords: COVID-19; Canada; Ontario; SARS-CoV-2; health administrative data; healthcare cost; respiratory infections; viruses.

 
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