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Emerg Infect Dis . Respiratory Virus Detection and Sequencing from SARS-CoV-2-Negative Rapid Antigen Tests

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2025 May;31(13):39-44.
doi: 10.3201/eid3113.241191.
Respiratory Virus Detection and Sequencing from SARS-CoV-2-Negative Rapid Antigen Tests

Emmanuela Jules, Charlie Decker, Brianna Jeanne Bixler, Alaa Ahmed, Zijing Carol Zhou, Itika Arora, Henok Tafesse, Hannah Dakanay, Andrei Bombin, Ethan Wang, Jessica Ingersoll, Kathy Bifulco, Jennifer K Frediani, Richard Parsons, Julie Sullivan, Morgan Greenleaf, Jesse J Waggoner, Greg S Martin, Wilbur A Lam, Anne Piantadosi
Free article Abstract

Genomic epidemiology offers insight into the transmission and evolution of respiratory viruses. We used metagenomic sequencing from negative SARS-CoV-2 rapid antigen tests to identify a wide range of respiratory viruses and generate full genome sequences. This process offers a streamlined mechanism for broad respiratory virus genomic surveillance.

Keywords: COVID-19; SARS-CoV-2; coronavirus disease; molecular epidemiology; public health surveillance; respiratory infections; respiratory tract infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

 
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