tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2020 Aug 4;26(11).
doi: 10.3201/eid2611.203219. Online ahead of print.
SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease
Ranawaka A P M Perera, Eugene Tso, Owen T Y Tsang, Dominic N C Tsang, Kitty Fung, Yonna W Y Leung, Alex W H Chin, Daniel K W Chu, Samuel M S Cheng, Leo L M Poon, Vivien W M Chuang, Malik Peiris
Abstract
We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory syndrome coronavirus 2 and subgenomic RNA were rarely detectable beyond 8 days after onset of illness. However, virus RNA was detectable for many weeks by reverse transcription PCR.
Keywords: COVID-19; China; Hong Kong; SARS-CoV-2; coronavirus; coronavirus disease; infectivity; mild disease; respiratory infections; severe acute respiratory syndrome coronavirus 2; subgenomic RNA; viral RNA load; virus culture; viruses; zoonoses.
. 2020 Aug 4;26(11).
doi: 10.3201/eid2611.203219. Online ahead of print.
SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease
Ranawaka A P M Perera, Eugene Tso, Owen T Y Tsang, Dominic N C Tsang, Kitty Fung, Yonna W Y Leung, Alex W H Chin, Daniel K W Chu, Samuel M S Cheng, Leo L M Poon, Vivien W M Chuang, Malik Peiris
- PMID: 32749957
- DOI: 10.3201/eid2611.203219
Abstract
We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory syndrome coronavirus 2 and subgenomic RNA were rarely detectable beyond 8 days after onset of illness. However, virus RNA was detectable for many weeks by reverse transcription PCR.
Keywords: COVID-19; China; Hong Kong; SARS-CoV-2; coronavirus; coronavirus disease; infectivity; mild disease; respiratory infections; severe acute respiratory syndrome coronavirus 2; subgenomic RNA; viral RNA load; virus culture; viruses; zoonoses.