tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2025 Jul 9;37(8).
doi: 10.3201/eid3108.250373. Online ahead of print.
Transmission Dynamics of Highly Pathogenic Avian Influenza A(H5N1) and A(H5N6) Viruses in Wild Birds, South Korea, 2023-2024
Ye-Ram Seo, Andrew Y Cho, Dong-Ju Kim, Young-Jae Si, Hye-Sung Jeong, Su-Woong Lee, Chang-Seon Song, Dong-Hun Lee
We analyzed 15 cases of highly pathogenic avian influenza (HPAI) clade 2.3.4.4b virus infections detected in wild birds in South Korea during September 2023-March 2024. We isolated and sequenced 8 H5N1 and 7 H5N6 viruses. We investigated spatiotemporal transmission dynamics by using a Bayesian discrete trait phylodynamic model that incorporated geographic and host species information. Our source-sink dynamics support introductions of H5N1 viruses from northern Japan to South Korea and subsequent spread through multiple regions in South Korea. The H5N6 viruses were most likely introduced into southwestern South Korea and spread northeastward. Wild waterfowl, especially wild ducks, played a key role in transmission of both H5N1 and H5N6 viruses. Our data showed multiple introductions and extensive spread of HPAI clade 2.3.4.4b viruses and bidirectional transmission between Japan and South Korea. Our results highlight the value of enhanced active surveillance for monitoring HPAI viruses, which can provide insight into preventing future outbreaks.
Keywords: H5N1; H5N6; Highly pathogenic avian influenza virus; South Korea; discrete trait analysis; influenza; phylodynamics; phylogeography analysis; respiratory infections; viruses; wild birds.
. 2025 Jul 9;37(8).
doi: 10.3201/eid3108.250373. Online ahead of print.
Transmission Dynamics of Highly Pathogenic Avian Influenza A(H5N1) and A(H5N6) Viruses in Wild Birds, South Korea, 2023-2024
Ye-Ram Seo, Andrew Y Cho, Dong-Ju Kim, Young-Jae Si, Hye-Sung Jeong, Su-Woong Lee, Chang-Seon Song, Dong-Hun Lee
- PMID: 40633556
- DOI: 10.3201/eid3108.250373
We analyzed 15 cases of highly pathogenic avian influenza (HPAI) clade 2.3.4.4b virus infections detected in wild birds in South Korea during September 2023-March 2024. We isolated and sequenced 8 H5N1 and 7 H5N6 viruses. We investigated spatiotemporal transmission dynamics by using a Bayesian discrete trait phylodynamic model that incorporated geographic and host species information. Our source-sink dynamics support introductions of H5N1 viruses from northern Japan to South Korea and subsequent spread through multiple regions in South Korea. The H5N6 viruses were most likely introduced into southwestern South Korea and spread northeastward. Wild waterfowl, especially wild ducks, played a key role in transmission of both H5N1 and H5N6 viruses. Our data showed multiple introductions and extensive spread of HPAI clade 2.3.4.4b viruses and bidirectional transmission between Japan and South Korea. Our results highlight the value of enhanced active surveillance for monitoring HPAI viruses, which can provide insight into preventing future outbreaks.
Keywords: H5N1; H5N6; Highly pathogenic avian influenza virus; South Korea; discrete trait analysis; influenza; phylodynamics; phylogeography analysis; respiratory infections; viruses; wild birds.