tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2022 Aug;28(8):1664-1668.
doi: 10.3201/eid2808.212530.
Zoonotic Threat of G4 Genotype Eurasian Avian-Like Swine Influenza A(H1N1) Viruses, China, 2020
Min Gu, Kaibiao Chen, Zhichuang Ge, Jun Jiao, Tianyu Cai, Suhan Liu, Xiaoquan Wang, Xinan Jiao, Daxin Peng, Xiufan Liu
Abstract
We investigated genetic and biologic characteristics of 2 Eurasian avian-like H1N1 swine influenza viruses from pigs in China that belong to the predominant G4 genotype. One swine isolate exhibited strikingly great homology to contemporaneous human Eurasian avian-like H1N1 isolates, preferential binding to the human-type receptor, and vigorous replication in mice without adaptation.
Keywords: China; Eurasian avian-like H1N1; G4 genotype; H1N1; influenza; swine influenza; viruses; zoonoses.
. 2022 Aug;28(8):1664-1668.
doi: 10.3201/eid2808.212530.
Zoonotic Threat of G4 Genotype Eurasian Avian-Like Swine Influenza A(H1N1) Viruses, China, 2020
Min Gu, Kaibiao Chen, Zhichuang Ge, Jun Jiao, Tianyu Cai, Suhan Liu, Xiaoquan Wang, Xinan Jiao, Daxin Peng, Xiufan Liu
- PMID: 35876682
- DOI: 10.3201/eid2808.212530
Abstract
We investigated genetic and biologic characteristics of 2 Eurasian avian-like H1N1 swine influenza viruses from pigs in China that belong to the predominant G4 genotype. One swine isolate exhibited strikingly great homology to contemporaneous human Eurasian avian-like H1N1 isolates, preferential binding to the human-type receptor, and vigorous replication in mice without adaptation.
Keywords: China; Eurasian avian-like H1N1; G4 genotype; H1N1; influenza; swine influenza; viruses; zoonoses.