tetano
Editor, Senior Moderator
merg Microbes Infect
. 2024 Dec 3:2432368.
doi: 10.1080/22221751.2024.2432368. Online ahead of print. Susceptibility of calf lung slice cultures to H5N1 influenza virus
Kate Guilfoyle[SUP] 1 [/SUP], Monica Mirolo[SUP] 2 [/SUP], Geert van Amerongen[SUP] 1 [/SUP], Guido van der Net[SUP] 1 [/SUP], Mara Sophie Lombardo[SUP] 2 [/SUP], Theresa Störk[SUP] 2 [/SUP], Guus Rimmelzwaan[SUP] 2 [/SUP], Martin Ludlow[SUP] 2 [/SUP], Albert Osterhaus[SUP] 2 [/SUP]
Affiliations
The current outbreak of HPAI H5N1 virus infections in dairy cattle in the USA underscores the need for easily accessible methods to rapidly assess host susceptibility for infection with known and emerging influenza viruses. Here we show that ex vivo lung slice cultures from calves provide a useful method to rapidly screen host susceptibility to a range of influenza A viruses.
Keywords: HPAI H5N1; cattle; influenza; lung slices; species susceptibility.
. 2024 Dec 3:2432368.
doi: 10.1080/22221751.2024.2432368. Online ahead of print. Susceptibility of calf lung slice cultures to H5N1 influenza virus
Kate Guilfoyle[SUP] 1 [/SUP], Monica Mirolo[SUP] 2 [/SUP], Geert van Amerongen[SUP] 1 [/SUP], Guido van der Net[SUP] 1 [/SUP], Mara Sophie Lombardo[SUP] 2 [/SUP], Theresa Störk[SUP] 2 [/SUP], Guus Rimmelzwaan[SUP] 2 [/SUP], Martin Ludlow[SUP] 2 [/SUP], Albert Osterhaus[SUP] 2 [/SUP]
Affiliations
- PMID: 39624917
- DOI: 10.1080/22221751.2024.2432368
The current outbreak of HPAI H5N1 virus infections in dairy cattle in the USA underscores the need for easily accessible methods to rapidly assess host susceptibility for infection with known and emerging influenza viruses. Here we show that ex vivo lung slice cultures from calves provide a useful method to rapidly screen host susceptibility to a range of influenza A viruses.
Keywords: HPAI H5N1; cattle; influenza; lung slices; species susceptibility.