tetano
Editor, Senior Moderator
Epidemiol Infect
. 2024 Dec 11:152:e166.
doi: 10.1017/S0950268824001687. Receiving three doses of inactivated or mRNA COVID-19 vaccines was associated with lower odds of long COVID symptoms among people with a history of SARS-CoV-2 infection in Hong Kong, China: a cross-sectional survey study
Chen Zheng[SUP] 1 [/SUP], Fuk-Yuen Yu[SUP] 2 [/SUP], Paul Shing-Fong Chan[SUP] 2 [/SUP], Fenghua Sun[SUP] 1 [/SUP], Xiang-Ke Chen[SUP] 3 [/SUP], Wendy Ya-Jun Huang[SUP] 4 5 [/SUP], Stephen Heung-Sang Wong[SUP] 6 [/SUP], Yuan Fang[SUP] 1 [/SUP], Zixin Wang[SUP] 2 [/SUP]
Affiliations
High prevalence of long COVID symptoms has emerged as a significant public health concern. This study investigated the associations between three doses of COVID-19 vaccines and the presence of any and ≥3 types of long COVID symptoms among people with a history of SARS-CoV-2 infection in Hong Kong, China. This is a secondary analysis of a cross-sectional online survey among Hong Kong adult residents conducted between June and August 2022. This analysis was based on a sub-sample of 1,542 participants with confirmed SARS-CoV-2 infection during the fifth wave of COVID-19 outbreak in Hong Kong (December 2021 to April 2022). Among the participants, 40.9% and 16.1% self-reported having any and ≥3 types of long COVID symptoms, respectively. After adjusting for significant variables related to sociodemographic characteristics, health conditions and lifestyles, and SARS-CoV-2 infection, receiving at least three doses of COVID-19 vaccines was associated with lower odds of reporting any long COVID symptoms comparing to receiving two doses (adjusted odds ratio [AOR]: 0.69, 95% CI: 0.54, 0.87, P = .002). Three doses of inactivated and mRNA vaccines had similar protective effects against long COVID symptoms. It is important to strengthen the coverage of COVID-19 vaccination booster doses, even in the post-pandemic era.
Keywords: Long COVID; booster; inactivated vaccines; mRNA vaccines; post-COVID-19 condition; post-acute sequelae of COVID-19; vaccination.
. 2024 Dec 11:152:e166.
doi: 10.1017/S0950268824001687. Receiving three doses of inactivated or mRNA COVID-19 vaccines was associated with lower odds of long COVID symptoms among people with a history of SARS-CoV-2 infection in Hong Kong, China: a cross-sectional survey study
Chen Zheng[SUP] 1 [/SUP], Fuk-Yuen Yu[SUP] 2 [/SUP], Paul Shing-Fong Chan[SUP] 2 [/SUP], Fenghua Sun[SUP] 1 [/SUP], Xiang-Ke Chen[SUP] 3 [/SUP], Wendy Ya-Jun Huang[SUP] 4 5 [/SUP], Stephen Heung-Sang Wong[SUP] 6 [/SUP], Yuan Fang[SUP] 1 [/SUP], Zixin Wang[SUP] 2 [/SUP]
Affiliations
- PMID: 39659228
- DOI: 10.1017/S0950268824001687
High prevalence of long COVID symptoms has emerged as a significant public health concern. This study investigated the associations between three doses of COVID-19 vaccines and the presence of any and ≥3 types of long COVID symptoms among people with a history of SARS-CoV-2 infection in Hong Kong, China. This is a secondary analysis of a cross-sectional online survey among Hong Kong adult residents conducted between June and August 2022. This analysis was based on a sub-sample of 1,542 participants with confirmed SARS-CoV-2 infection during the fifth wave of COVID-19 outbreak in Hong Kong (December 2021 to April 2022). Among the participants, 40.9% and 16.1% self-reported having any and ≥3 types of long COVID symptoms, respectively. After adjusting for significant variables related to sociodemographic characteristics, health conditions and lifestyles, and SARS-CoV-2 infection, receiving at least three doses of COVID-19 vaccines was associated with lower odds of reporting any long COVID symptoms comparing to receiving two doses (adjusted odds ratio [AOR]: 0.69, 95% CI: 0.54, 0.87, P = .002). Three doses of inactivated and mRNA vaccines had similar protective effects against long COVID symptoms. It is important to strengthen the coverage of COVID-19 vaccination booster doses, even in the post-pandemic era.
Keywords: Long COVID; booster; inactivated vaccines; mRNA vaccines; post-COVID-19 condition; post-acute sequelae of COVID-19; vaccination.