tetano
Editor, Senior Moderator
PLoS One. 2016 Aug 17;11(8):e0161195. doi: 10.1371/journal.pone.0161195. eCollection 2016.
[h=1]Epidemiological and Virological Characterization of Influenza B Virus Infections.[/h] Sharabi S[SUP]1,[/SUP][SUP]2[/SUP], Drori Y[SUP]1,[/SUP][SUP]2[/SUP], Micheli M[SUP]1[/SUP], Friedman N[SUP]1,[/SUP][SUP]2[/SUP], Orzitzer S[SUP]1[/SUP], Bassal R[SUP]3[/SUP], Glatman-Freedman A[SUP]3,[/SUP][SUP]4[/SUP], Shohat T[SUP]2,[/SUP][SUP]3[/SUP], Mendelson E[SUP]1,[/SUP][SUP]2[/SUP], Hindiyeh M[SUP]1,[/SUP][SUP]2[/SUP], Mandelboim M[SUP]1,[/SUP][SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] While influenza A viruses comprise a heterogeneous group of clinically relevant influenza viruses, influenza B viruses form a more homogeneous cluster, divided mainly into two lineages: Victoria and Yamagata. This divergence has complicated seasonal influenza vaccine design, which traditionally contained two seasonal influenza A virus strains and one influenza B virus strain. We examined the distribution of the two influenza B virus lineages in Israel, between 2011-2014, in hospitalized and in non-hospitalized (community) influenza B virus-infected patients. We showed that influenza B virus infections can lead to hospitalization and demonstrated that during some winter seasons, both influenza B virus lineages circulated simultaneously in Israel. We further show that the influenza B virus Yamagata lineage was dominant, circulating in the county in the last few years of the study period, consistent with the anti-Yamagata influenza B virus antibodies detected in the serum samples of affected individuals residing in Israel in the year 2014. Interestingly, we found that elderly people were particularly vulnerable to Yamagata lineage influenza B virus infections.
PMID: 27533045 DOI: 10.1371/journal.pone.0161195
[PubMed - in process] Free full text
[h=1]Epidemiological and Virological Characterization of Influenza B Virus Infections.[/h] Sharabi S[SUP]1,[/SUP][SUP]2[/SUP], Drori Y[SUP]1,[/SUP][SUP]2[/SUP], Micheli M[SUP]1[/SUP], Friedman N[SUP]1,[/SUP][SUP]2[/SUP], Orzitzer S[SUP]1[/SUP], Bassal R[SUP]3[/SUP], Glatman-Freedman A[SUP]3,[/SUP][SUP]4[/SUP], Shohat T[SUP]2,[/SUP][SUP]3[/SUP], Mendelson E[SUP]1,[/SUP][SUP]2[/SUP], Hindiyeh M[SUP]1,[/SUP][SUP]2[/SUP], Mandelboim M[SUP]1,[/SUP][SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] While influenza A viruses comprise a heterogeneous group of clinically relevant influenza viruses, influenza B viruses form a more homogeneous cluster, divided mainly into two lineages: Victoria and Yamagata. This divergence has complicated seasonal influenza vaccine design, which traditionally contained two seasonal influenza A virus strains and one influenza B virus strain. We examined the distribution of the two influenza B virus lineages in Israel, between 2011-2014, in hospitalized and in non-hospitalized (community) influenza B virus-infected patients. We showed that influenza B virus infections can lead to hospitalization and demonstrated that during some winter seasons, both influenza B virus lineages circulated simultaneously in Israel. We further show that the influenza B virus Yamagata lineage was dominant, circulating in the county in the last few years of the study period, consistent with the anti-Yamagata influenza B virus antibodies detected in the serum samples of affected individuals residing in Israel in the year 2014. Interestingly, we found that elderly people were particularly vulnerable to Yamagata lineage influenza B virus infections.
PMID: 27533045 DOI: 10.1371/journal.pone.0161195
[PubMed - in process] Free full text