tetano
Editor, Senior Moderator
J Med Virol. 2015 Nov 23. doi: 10.1002/jmv.24435. [Epub ahead of print]
[h=1]Epidemiology of 11 respiratory RNA viruses in a cohort of hospitalized children in Riyadh, Saudi Arabia.[/h] Amer HM[SUP]1,[/SUP][SUP]2[/SUP], Alshaman MS[SUP]1[/SUP], Farrag MA[SUP]1[/SUP], Hamad ME[SUP]1[/SUP], Alsaadi MM[SUP]3[/SUP], Almajhdi FN[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Respiratory tract infections are a principal cause of illness and mortality in children worldwide and mostly caused by viruses. In this study, the epidemiology of 11 respiratory RNA viruses was investigated in a cohort of hospitalized children at a tertiary referral center in Riyadh from February 2008 to March 2009 using conventional and real-time monoplex RT-PCR assays. Among 174 nasopharyngeal aspirates, respiratory syncytial virus (RSV) was detected in 39 samples (22.41%), influenza A virus in 34 (19.54%), metapneumovirus (MPV) in 19 (10.92%), coronaviruses in 14 (8.05%), and parainfluenza viruses (PIVs) in 11 (6.32%). RSV, PIVs and coronaviruses were most prevalent in infants less than 6 months old, MPV and influenza A virus were more prominent in children aged 7-24 and 25-60 months, respectively. The majority of the viruses were identified during winter with two peaks observed in March 2008 and January 2009. The presented data warrants further investigation to understand the epidemiology of respiratory viruses in Saudi Arabia on spatial and temporal basis. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Epidemiology; Riyadh; molecular tools; prevalence; respiratory viruses
PMID: 26595650 [PubMed - as supplied by publisher]
[h=1]Epidemiology of 11 respiratory RNA viruses in a cohort of hospitalized children in Riyadh, Saudi Arabia.[/h] Amer HM[SUP]1,[/SUP][SUP]2[/SUP], Alshaman MS[SUP]1[/SUP], Farrag MA[SUP]1[/SUP], Hamad ME[SUP]1[/SUP], Alsaadi MM[SUP]3[/SUP], Almajhdi FN[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Respiratory tract infections are a principal cause of illness and mortality in children worldwide and mostly caused by viruses. In this study, the epidemiology of 11 respiratory RNA viruses was investigated in a cohort of hospitalized children at a tertiary referral center in Riyadh from February 2008 to March 2009 using conventional and real-time monoplex RT-PCR assays. Among 174 nasopharyngeal aspirates, respiratory syncytial virus (RSV) was detected in 39 samples (22.41%), influenza A virus in 34 (19.54%), metapneumovirus (MPV) in 19 (10.92%), coronaviruses in 14 (8.05%), and parainfluenza viruses (PIVs) in 11 (6.32%). RSV, PIVs and coronaviruses were most prevalent in infants less than 6 months old, MPV and influenza A virus were more prominent in children aged 7-24 and 25-60 months, respectively. The majority of the viruses were identified during winter with two peaks observed in March 2008 and January 2009. The presented data warrants further investigation to understand the epidemiology of respiratory viruses in Saudi Arabia on spatial and temporal basis. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Epidemiology; Riyadh; molecular tools; prevalence; respiratory viruses
PMID: 26595650 [PubMed - as supplied by publisher]