tetano
Editor, Senior Moderator
J Infect Dis. 2012 Dec;206 Suppl 1:S53-60. doi: 10.1093/infdis/jis530.
Epidemiology, seasonality, and burden of influenza and influenza-like illness in urban and rural kenya, 2007-2010.
Katz MA, Lebo E, Emukule G, Njuguna HN, Aura B, Cosmas L, Audi A, Junghae M, Waiboci LW, Olack B, Bigogo G, Njenga MK, Feikin DR, Breiman RF.
Source
Influenza Program, Kenya Medical Research Institute/Centers for Disease Control and Prevention Public Health and Research Collaboration, Kenya.
Abstract
Background. The epidemiology and burden of influenza remain poorly defined in sub-Saharan Africa. Since 2005, the Kenya Medical Research Institute and Centers for Disease Control and Prevention-Kenya have conducted population-based infectious disease surveillance in Kibera, an urban informal settlement in Nairobi, and in Lwak, a rural community in western Kenya. Methods. Nasopharyngeal and oropharyngeal swab specimens were obtained from patients who attended the study clinic and had acute lower respiratory tract (LRT) illness. Specimens were tested for influenza virus by real-time reverse-transcription polymerase chain reaction. We adjusted the incidence of influenza-associated acute LRT illness to account for patients with acute LRT illness who attended the clinic but were not sampled. Results. From March 2007 through February 2010, 4140 cases of acute LRT illness were evaluated in Kibera, and specimens were collected from 1197 (27%); 319 (27%) were positive for influenza virus. In Lwak, there were 6733 cases of acute LRT illness, and specimens were collected from 1641 (24%); 359 (22%) were positive for influenza virus. The crude and adjusted rates of medically attended influenza-associated acute LRT illness were 6.9 and 13.6 cases per 1000 person-years, respectively, in Kibera, and 5.6 and 23.0 cases per 1000 person-years, respectively, in Lwak. In both sites, rates of influenza-associated acute LRT illness were highest among children <2 years old and lowest among adults ≥50 years old. Conclusion. In Kenya, the incidence of influenza-associated acute LRT illness was high in both rural and urban settings, particularly among the most vulnerable age groups.
PMID:
23169973
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23169973
Epidemiology, seasonality, and burden of influenza and influenza-like illness in urban and rural kenya, 2007-2010.
Katz MA, Lebo E, Emukule G, Njuguna HN, Aura B, Cosmas L, Audi A, Junghae M, Waiboci LW, Olack B, Bigogo G, Njenga MK, Feikin DR, Breiman RF.
Source
Influenza Program, Kenya Medical Research Institute/Centers for Disease Control and Prevention Public Health and Research Collaboration, Kenya.
Abstract
Background. The epidemiology and burden of influenza remain poorly defined in sub-Saharan Africa. Since 2005, the Kenya Medical Research Institute and Centers for Disease Control and Prevention-Kenya have conducted population-based infectious disease surveillance in Kibera, an urban informal settlement in Nairobi, and in Lwak, a rural community in western Kenya. Methods. Nasopharyngeal and oropharyngeal swab specimens were obtained from patients who attended the study clinic and had acute lower respiratory tract (LRT) illness. Specimens were tested for influenza virus by real-time reverse-transcription polymerase chain reaction. We adjusted the incidence of influenza-associated acute LRT illness to account for patients with acute LRT illness who attended the clinic but were not sampled. Results. From March 2007 through February 2010, 4140 cases of acute LRT illness were evaluated in Kibera, and specimens were collected from 1197 (27%); 319 (27%) were positive for influenza virus. In Lwak, there were 6733 cases of acute LRT illness, and specimens were collected from 1641 (24%); 359 (22%) were positive for influenza virus. The crude and adjusted rates of medically attended influenza-associated acute LRT illness were 6.9 and 13.6 cases per 1000 person-years, respectively, in Kibera, and 5.6 and 23.0 cases per 1000 person-years, respectively, in Lwak. In both sites, rates of influenza-associated acute LRT illness were highest among children <2 years old and lowest among adults ≥50 years old. Conclusion. In Kenya, the incidence of influenza-associated acute LRT illness was high in both rural and urban settings, particularly among the most vulnerable age groups.
PMID:
23169973
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23169973