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Estimating burden of influenza-associated influenza-like illness and severe acute respiratory infection at public health care facilities in Romania du

tetano

Editor, Senior Moderator
Influenza Other Respir Viruses. 2017 Nov 16. doi: 10.1111/irv.12525. [Epub ahead of print]
[h=1]Estimating burden of influenza-associated influenza-like illness and severe acute respiratory infection at public health care facilities in Romania during the 2011/12-2015/16 influenza seasons.[/h] Gefenaite G[SUP]1,[/SUP][SUP]2[/SUP], Pistol A[SUP]3[/SUP], Popescu R[SUP]3[/SUP], Popovici O[SUP]3[/SUP], Ciurea D[SUP]4[/SUP], Dolk C[SUP]1,[/SUP][SUP]5[/SUP], Jit M[SUP]6[/SUP], Gross D[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Influenza is responsible for substantial morbidity and mortality, but there is limited information on reliable disease burden estimates, especially from middle-income countries in the WHO European Region.
[h=4]OBJECTIVES:[/h] To estimate the incidence of medically attended influenza-associated influenza-like illness (ILI) and hospitalizations due to severe acute respiratory infection (SARI) presenting to public health care facilities in Romania.
[h=4]PATIENTS/METHODS:[/h] Sentinel influenza surveillance data for ILI and SARI from 2011/12-2015/16, including virological data, was used to estimate influenza-associated ILI and SARI incidence/100000 and their 95% confidence intervals (95% CI).
[h=4]RESULTS:[/h] The overall annual incidence of ILI and influenza-associated ILI per 100.000 persons in Romania varied between 68 (95%CI 61 to 76) and 318 (95%CI 298 to 338) and between 23 (95%CI 19 to 29) and 189 (95%CI 149 to 240) respectively. The highest ILI and influenza incidence was among children 0 to 4 years old. We estimated that SARI incidence per 100.000 persons was 6 (95%CI 5 to 7) to 9 (95%CI 8 to 10), of which 2 (95%CI 1 to 2) to 3 (95%CI 2 to 4) were due to influenza. Up to 0.3% of the Romanian population were annually reported with ILI, and 0.01% was hospitalized with SARI, of which as much as one third could be explained by influenza.
[h=4]CONCLUSIONS:[/h] This evaluation was the first study estimating influenza burden in Romania. We found that during each influenza season, a substantial number of persons in Romania suffer from influenza related ILI or are hospitalized due to influenza-associated SARI. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.


[h=4]KEYWORDS:[/h] Burden; Influenza-like illness; Severe acute respiratory infection

PMID: 29144598 DOI: 10.1111/irv.12525
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