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Estimating the burden of Influenza-associated hospitalizations and deaths in Central America

tetano

Editor, Senior Moderator
Influenza Other Respir Viruses. 2016 Mar 4. doi: 10.1111/irv.12385. [Epub ahead of print]
[h=1]Estimating the burden of Influenza-associated hospitalizations and deaths in Central America.[/h] Descalzo MA[SUP]1[/SUP], Clara W[SUP]2[/SUP], Guzm?n G[SUP]3[/SUP], Mena R[SUP]4[/SUP], Armero J[SUP]5[/SUP], Lara B[SUP]6[/SUP], Saenz C[SUP]7[/SUP], Arag?n A[SUP]1[/SUP], Chac?n R[SUP]1[/SUP], El-Omeiri N[SUP]8[/SUP], M?ndez-Rico J[SUP]8[/SUP], Cerpa M[SUP]8[/SUP], Palekar R[SUP]8,[/SUP][SUP]9[/SUP], Jara J[SUP]1[/SUP], Azziz-Baumgartner E[SUP]9[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Influenza is a preventable disease whose burden should be well documented, a necessary step in mobilizing vaccine program staff, providers and influenza vaccine target groups. We estimate the incidence of influenza hospitalizations from five Central America countries. We performed a meta-analysis of influenza-associated hospitalizations and in-hospital deaths. The highest annual incidence was observed among children aged <5 years (136 influenza-associated hospitalizations per 100,000 persons). Annually 7,625-11,289 influenza-associated hospitalizations and 352-594 deaths occurred in the sub-region. Our results suggest that a substantive number of persons are annually hospitalized because of influenza. Health officials should estimate how many illnesses could be averted through increased influenza vaccination. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.


[h=4]KEYWORDS:[/h] America; burden of disease; hospitalizations; influenza; meta-analysis; mortality; multiplier model

PMID: 26946216 [PubMed - as supplied by publisher]
 
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