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Estimation of the burden of flu-association influenza-like illness visits on total clinic visits through the sentinel influenza monitoring system in S

tetano

Editor, Senior Moderator
Epidemiol Infect. 2018 Sep 10:1-7. doi: 10.1017/S0950268818002418. [Epub ahead of print]
[h=1]Estimation of the burden of flu-association influenza-like illness visits on total clinic visits through the sentinel influenza monitoring system in Senegal during the 2013-2015 influenza seasons.[/h] Niang MN[SUP]1[/SUP], Barry MA[SUP]2[/SUP], Talla C[SUP]2[/SUP], Mbengue A[SUP]1[/SUP], Sarr FD[SUP]2[/SUP], Ba IO[SUP]3[/SUP], Hedible BG[SUP]2[/SUP], Ndoye B[SUP]4[/SUP], Vray M[SUP]2[/SUP], Dia N[SUP]1[/SUP]; 4S Network Group.
[h=3]Author information[/h]

[h=3]Abstract[/h] Knowing the burden of influenza is helpful for policy decisions. Here we estimated the contribution of influenza-like illness (ILI) visits associated with laboratory-confirmed influenza among all clinic visits in a Senegal sentinel network. ILI data from ten sentinel sites were collected from January 2013 to December 2015. ILI was defined as an axillary measured fever of more than 37.5 ?C with a cough or a sore throat. Collected nasopharyngeal swabs were tested for influenza viruses by rRT-PCR. Influenza-associated ILI was defined as ILI with laboratory-confirmed influenza. For the influenza disease burden estimation, we used all-case outpatient visits during the study period who sought care at selected sites. Of 4030 ILI outpatients tested, 1022 were influenza positive. The estimated proportional contribution of influenza-associated ILI was, per 100 outpatients, 1.2 (95% CI 1.1-1.3), 0.32 (95% CI 0.28-0.35), 1.11 (95% CI 1.05-1.16) during 2013, 2014, 2015, respectively. The age-specific outpatient visits proportions of influenza-associated ILI were higher among children under 5 years (0.68%, 95% CI: 0.62-0.70). The predominant virus during years 2013 and 2015 was influenza B while A/H3N2 subtype was predominant during 2014. Influenza viruses cause a substantial burden of outpatient visits particularly among children under 5 of age in Senegal and highlight the need of vaccination in risk groups.


[h=4]KEYWORDS:[/h] Burden; Senegal; children; influenza; influenza-like illness; outpatient visit

PMID: 30196797 DOI: 10.1017/S0950268818002418
 
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