tetano
Editor, Senior Moderator
Comp Immunol Microbiol Infect Dis. 2019 Jun;64:153-158. doi: 10.1016/j.cimid.2019.03.004. Epub 2019 Mar 8.
[h=1]Etiology and characteristics of community-acquired pneumonia in an influenza epidemic period.[/h] Lin C[SUP]1[/SUP], Chen H[SUP]2[/SUP], He P[SUP]3[/SUP], Li Y[SUP]4[/SUP], Ke C[SUP]5[/SUP], Jiao X[SUP]6[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]PURPOSE:[/h] The etiology of community-acquired pneumonia (CAP) in hospital patients is often ambiguous due to the limited pathogen detection. Lack of a microbiological diagnosis impairs precision treatment in CAP.
[h=4]METHODS:[/h] Specimens collected from the lower respiratory tract of 195 CAP patients, viruses were measured by the Single-plex real-time PCR assay and the conventional culture method was exploited for bacteria.
[h=4]RESULTS:[/h] Among the 195 patients, there were 46 (23.59%) pure bacterial infections, 20 (10.26%) yeast infections, 32 (16.41%) pure viral infections, 8 (4.10%) viral-yeast co-infections, and 17 (8.72%) viral-bacterial co-infections. The two most abundant bacteria were Acinetobacter baumannii and klebsiella pneumoniae, whereas the most common virus was influenza A.
[h=4]CONCLUSIONS:[/h] Non-influenza respiratory microorganisms frequently co-circulated during the epidemic peaks of influenza, which easily being ignored in CAP therapy. In patients with bacterial and viral co-infections, identifying the etiologic agent is crucial for patient's therapy.
Copyright ? 2019 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Co-infections; Community-acquired pneumonia; Influenza; Respiratory virus; bacterial/Yeast infection
PMID: 31174691 DOI: 10.1016/j.cimid.2019.03.004
[h=1]Etiology and characteristics of community-acquired pneumonia in an influenza epidemic period.[/h] Lin C[SUP]1[/SUP], Chen H[SUP]2[/SUP], He P[SUP]3[/SUP], Li Y[SUP]4[/SUP], Ke C[SUP]5[/SUP], Jiao X[SUP]6[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]PURPOSE:[/h] The etiology of community-acquired pneumonia (CAP) in hospital patients is often ambiguous due to the limited pathogen detection. Lack of a microbiological diagnosis impairs precision treatment in CAP.
[h=4]METHODS:[/h] Specimens collected from the lower respiratory tract of 195 CAP patients, viruses were measured by the Single-plex real-time PCR assay and the conventional culture method was exploited for bacteria.
[h=4]RESULTS:[/h] Among the 195 patients, there were 46 (23.59%) pure bacterial infections, 20 (10.26%) yeast infections, 32 (16.41%) pure viral infections, 8 (4.10%) viral-yeast co-infections, and 17 (8.72%) viral-bacterial co-infections. The two most abundant bacteria were Acinetobacter baumannii and klebsiella pneumoniae, whereas the most common virus was influenza A.
[h=4]CONCLUSIONS:[/h] Non-influenza respiratory microorganisms frequently co-circulated during the epidemic peaks of influenza, which easily being ignored in CAP therapy. In patients with bacterial and viral co-infections, identifying the etiologic agent is crucial for patient's therapy.
Copyright ? 2019 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Co-infections; Community-acquired pneumonia; Influenza; Respiratory virus; bacterial/Yeast infection
PMID: 31174691 DOI: 10.1016/j.cimid.2019.03.004