tetano
Editor, Senior Moderator
Eur Arch Otorhinolaryngol
. 2021 May 7.
doi: 10.1007/s00405-021-06839-w. Online ahead of print.
Self-reported smell and taste recovery in coronavirus disease 2019 patients: a one-year prospective study
Paolo Boscolo-Rizzo[SUP] 1 [/SUP], Francesco Guida[SUP] 2 [/SUP], Jerry Polesel[SUP] 3 [/SUP], Alberto Vito Marcuzzo[SUP] 2 [/SUP], Paolo Antonucci[SUP] 2 [/SUP], Vincenzo Capriotti[SUP] 4 [/SUP], Erica Sacchet[SUP] 2 [/SUP], Fiordaliso Cragnolini[SUP] 2 [/SUP], Andrea D'Alessandro[SUP] 2 [/SUP], Enrico Zanelli[SUP] 2 [/SUP], Riccardo Marzolino[SUP] 2 [/SUP], Chiara Lazzarin[SUP] 2 [/SUP], Margherita Tofanelli[SUP] 2 [/SUP], Nicoletta Gardenal[SUP] 2 [/SUP], Daniele Borsetto[SUP] 5 [/SUP], Claire Hopkins[SUP] 6 [/SUP], Luigi Angelo Vaira[SUP] 7 [/SUP], Giancarlo Tirelli[SUP] 2 [/SUP]
Affiliations
Abstract
Purpose: The aim of the present study was to estimate the 1 year prevalence and recovery rate of self-reported chemosensory dysfunction in a series of subjects with previous mild-to-moderate symptomatic COVID-19.
Methods: Prospective study based on the SNOT-22, item "sense of smell or taste" and additional outcomes.
Results: 268/315 patients (85.1%) completing the survey at baseline also completed the follow-up interview. The 12 months prevalence of self-reported COVID-19 associated chemosensory dysfunction was 21.3% (95% CI 16.5-26.7%). Of the 187 patients who complained of COVID-19 associated chemosensory dysfunction at baseline, 130 (69.5%; 95% CI 62.4-76.0%) reported complete resolution of smell or taste impairment, 41 (21.9%) reported a decrease in the severity, and 16 (8.6%) reported the symptom was unchanged or worse 1 year after onset. The risk of persistence was higher for patients reporting a baseline SNOT-22 score ? 4 (OR = 3.32; 95% CI 1.32-8.36) as well as for those requiring ? 22 days for a negative swab (OR = 2.18; 95% CI 1.12-4.27).
Conclusion: A substantial proportion of patients with previous mild-to-moderate symptomatic COVID-19 characterized by new onset of chemosensory dysfunction still complained on altered sense of smell or taste 1 year after the onset.
Keywords: Anosmia; COVID-19; Coronavirus; Outcome; SARS-CoV-2; Smell; Taste.
. 2021 May 7.
doi: 10.1007/s00405-021-06839-w. Online ahead of print.
Self-reported smell and taste recovery in coronavirus disease 2019 patients: a one-year prospective study
Paolo Boscolo-Rizzo[SUP] 1 [/SUP], Francesco Guida[SUP] 2 [/SUP], Jerry Polesel[SUP] 3 [/SUP], Alberto Vito Marcuzzo[SUP] 2 [/SUP], Paolo Antonucci[SUP] 2 [/SUP], Vincenzo Capriotti[SUP] 4 [/SUP], Erica Sacchet[SUP] 2 [/SUP], Fiordaliso Cragnolini[SUP] 2 [/SUP], Andrea D'Alessandro[SUP] 2 [/SUP], Enrico Zanelli[SUP] 2 [/SUP], Riccardo Marzolino[SUP] 2 [/SUP], Chiara Lazzarin[SUP] 2 [/SUP], Margherita Tofanelli[SUP] 2 [/SUP], Nicoletta Gardenal[SUP] 2 [/SUP], Daniele Borsetto[SUP] 5 [/SUP], Claire Hopkins[SUP] 6 [/SUP], Luigi Angelo Vaira[SUP] 7 [/SUP], Giancarlo Tirelli[SUP] 2 [/SUP]
Affiliations
- PMID: 33963433
- DOI: 10.1007/s00405-021-06839-w
Abstract
Purpose: The aim of the present study was to estimate the 1 year prevalence and recovery rate of self-reported chemosensory dysfunction in a series of subjects with previous mild-to-moderate symptomatic COVID-19.
Methods: Prospective study based on the SNOT-22, item "sense of smell or taste" and additional outcomes.
Results: 268/315 patients (85.1%) completing the survey at baseline also completed the follow-up interview. The 12 months prevalence of self-reported COVID-19 associated chemosensory dysfunction was 21.3% (95% CI 16.5-26.7%). Of the 187 patients who complained of COVID-19 associated chemosensory dysfunction at baseline, 130 (69.5%; 95% CI 62.4-76.0%) reported complete resolution of smell or taste impairment, 41 (21.9%) reported a decrease in the severity, and 16 (8.6%) reported the symptom was unchanged or worse 1 year after onset. The risk of persistence was higher for patients reporting a baseline SNOT-22 score ? 4 (OR = 3.32; 95% CI 1.32-8.36) as well as for those requiring ? 22 days for a negative swab (OR = 2.18; 95% CI 1.12-4.27).
Conclusion: A substantial proportion of patients with previous mild-to-moderate symptomatic COVID-19 characterized by new onset of chemosensory dysfunction still complained on altered sense of smell or taste 1 year after the onset.
Keywords: Anosmia; COVID-19; Coronavirus; Outcome; SARS-CoV-2; Smell; Taste.