tetano
Editor, Senior Moderator
Eur Heart J Case Rep
. 2022 Jan 24;6(2):ytac006.
doi: 10.1093/ehjcr/ytac006. eCollection 2022 Feb.
Case report: Mechanical mitral prosthetic valve thrombosis in the context of COVID-19 despite effective anticoagulation
Clarisse Jeckelmann[SUP] 1 [/SUP], Bojan Djokic[SUP] 2 [/SUP], Valérie Duchatelle[SUP] 2 [/SUP], Grégoire Girod[SUP] 1 2 3 [/SUP]
Affiliations
Abstract
Background: The SARS-CoV2 virus has been an emerging virus since December 2019 and is the cause of a global pandemic whose clinical manifestations extend far beyond respiratory disease.
Case summary: A patient with severe coronavirus disease 2019 respiratory infection, carrying a mechanical mitral valve and under anticoagulation, was admitted to our cardiology department because of a new atrial fibrillation, which turned out to be related to thrombosis of the mitral mechanical valve.
Conclusion: The pro-coagulant effect of the SARS-CoV2 virus does not spare patients at risk of thrombosis, even under effective anticoagulation. In patients with mechanical valves under vitamin K antagonist treatment, there is a high risk of thrombus formation. The treatment is based on thrombolysis by therapeutic anticoagulation, fibrinolysis, or surgery depending on the size, composition of thrombus, and clinical manifestation.
Keywords: Case report; Coronavirus; Mechanical mitral valve thrombosis; Thrombolysis anticoagulation.
. 2022 Jan 24;6(2):ytac006.
doi: 10.1093/ehjcr/ytac006. eCollection 2022 Feb.
Case report: Mechanical mitral prosthetic valve thrombosis in the context of COVID-19 despite effective anticoagulation
Clarisse Jeckelmann[SUP] 1 [/SUP], Bojan Djokic[SUP] 2 [/SUP], Valérie Duchatelle[SUP] 2 [/SUP], Grégoire Girod[SUP] 1 2 3 [/SUP]
Affiliations
- PMID: 35146323
- PMCID: PMC8807240
- DOI: 10.1093/ehjcr/ytac006
Abstract
Background: The SARS-CoV2 virus has been an emerging virus since December 2019 and is the cause of a global pandemic whose clinical manifestations extend far beyond respiratory disease.
Case summary: A patient with severe coronavirus disease 2019 respiratory infection, carrying a mechanical mitral valve and under anticoagulation, was admitted to our cardiology department because of a new atrial fibrillation, which turned out to be related to thrombosis of the mitral mechanical valve.
Conclusion: The pro-coagulant effect of the SARS-CoV2 virus does not spare patients at risk of thrombosis, even under effective anticoagulation. In patients with mechanical valves under vitamin K antagonist treatment, there is a high risk of thrombus formation. The treatment is based on thrombolysis by therapeutic anticoagulation, fibrinolysis, or surgery depending on the size, composition of thrombus, and clinical manifestation.
Keywords: Case report; Coronavirus; Mechanical mitral valve thrombosis; Thrombolysis anticoagulation.