tetano
Editor, Senior Moderator
Eur Heart J Case Rep
. 2023 Dec 4;7(12):ytad594.
doi: 10.1093/ehjcr/ytad594. eCollection 2023 Dec. Multisystem inflammatory syndrome in adults with cardiac engagement: a case report and literature review
Linda Massoud[SUP] 1 [/SUP], Katarina Westling[SUP] 2 3 [/SUP], Marie Fischer[SUP] 4 [/SUP], Emil Najjar[SUP] 1 5 [/SUP]
Affiliations
Background: Following infection with severe acute respiratory syndrome coronavirus, a post-infectious multisystem inflammatory syndrome in adults (MIS-A) has been identified. It affects multiple organ systems and can lead to multi-organic failure.
Case summary: This case report describes a patient with MIS-A with significant cardiac involvement including peri-myocarditis, pulmonary hypertension, right-sided heart failure, tricuspid regurgitation, and cardiogenic shock. After being diagnosed and treated correctly for MIS-A, the patient recovered completely, without any cardiac sequelae.
Discussion: The hyperinflammation in MIS-A can have cardiac engagement. Although more research is required to further clarify the underlying mechanisms, prompt diagnosis and anti-inflammatory treatment are crucial for better outcomes and cardiac recovery.
Keywords: Cardiogenic shock; Case report; Multisystem inflammatory syndrome in adults; Right ventricular heart failure; Tricuspid regurgitation.
. 2023 Dec 4;7(12):ytad594.
doi: 10.1093/ehjcr/ytad594. eCollection 2023 Dec. Multisystem inflammatory syndrome in adults with cardiac engagement: a case report and literature review
Linda Massoud[SUP] 1 [/SUP], Katarina Westling[SUP] 2 3 [/SUP], Marie Fischer[SUP] 4 [/SUP], Emil Najjar[SUP] 1 5 [/SUP]
Affiliations
- PMID: 38638274
- PMCID: PMC11024807
- DOI: 10.1093/ehjcr/ytad594
Background: Following infection with severe acute respiratory syndrome coronavirus, a post-infectious multisystem inflammatory syndrome in adults (MIS-A) has been identified. It affects multiple organ systems and can lead to multi-organic failure.
Case summary: This case report describes a patient with MIS-A with significant cardiac involvement including peri-myocarditis, pulmonary hypertension, right-sided heart failure, tricuspid regurgitation, and cardiogenic shock. After being diagnosed and treated correctly for MIS-A, the patient recovered completely, without any cardiac sequelae.
Discussion: The hyperinflammation in MIS-A can have cardiac engagement. Although more research is required to further clarify the underlying mechanisms, prompt diagnosis and anti-inflammatory treatment are crucial for better outcomes and cardiac recovery.
Keywords: Cardiogenic shock; Case report; Multisystem inflammatory syndrome in adults; Right ventricular heart failure; Tricuspid regurgitation.