tetano
Editor, Senior Moderator
Eur J Case Rep Intern Med
. 2020 May 13;7(6):001710.
doi: 10.12890/2020_001710. eCollection 2020.
Acalculous Acute Pancreatitis in a COVID-19 Patient
Pedro Antunes Meireles[SUP] 1 2 [/SUP], Filipe Bessa[SUP] 1 [/SUP], Pedro Gaspar[SUP] 1 3 [/SUP], In?s Parreira[SUP] 1 [/SUP], Virg?lio Dias Silva[SUP] 1 4 [/SUP], Catarina Mota[SUP] 1 3 [/SUP], Lourdes Alvoeiro[SUP] 1 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) is a multisystemic condition caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with manifestations ranging from mild upper respiratory symptoms to cytokine storm causing acute respiratory distress syndrome. Pancreatic exocrine tissue and endocrine islets both express angiotensin-converting enzyme 2 (ACE2), the proven receptor for SARS-CoV-2 cell internalization. An increase in pancreatic enzymes has been increasingly recognized in patients with COVID-19, but little is known about the real prevalence of acute pancreatitis in this population. We report a case of acute acalculous pancreatitis in a COVID-19 patient.
Learning points: Acute pancreatitis may be a manifestation of SARS-CoV-2 infection.Future studies must address the real impact of pancreatic involvement in COVID-19 patients.
Keywords: SARS-CoV-2; acute pancreatitis; amylase; lipase.
. 2020 May 13;7(6):001710.
doi: 10.12890/2020_001710. eCollection 2020.
Acalculous Acute Pancreatitis in a COVID-19 Patient
Pedro Antunes Meireles[SUP] 1 2 [/SUP], Filipe Bessa[SUP] 1 [/SUP], Pedro Gaspar[SUP] 1 3 [/SUP], In?s Parreira[SUP] 1 [/SUP], Virg?lio Dias Silva[SUP] 1 4 [/SUP], Catarina Mota[SUP] 1 3 [/SUP], Lourdes Alvoeiro[SUP] 1 [/SUP]
Affiliations
- PMID: 32523925
- PMCID: PMC7279899
- DOI: 10.12890/2020_001710
Abstract
Coronavirus disease 2019 (COVID-19) is a multisystemic condition caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with manifestations ranging from mild upper respiratory symptoms to cytokine storm causing acute respiratory distress syndrome. Pancreatic exocrine tissue and endocrine islets both express angiotensin-converting enzyme 2 (ACE2), the proven receptor for SARS-CoV-2 cell internalization. An increase in pancreatic enzymes has been increasingly recognized in patients with COVID-19, but little is known about the real prevalence of acute pancreatitis in this population. We report a case of acute acalculous pancreatitis in a COVID-19 patient.
Learning points: Acute pancreatitis may be a manifestation of SARS-CoV-2 infection.Future studies must address the real impact of pancreatic involvement in COVID-19 patients.
Keywords: SARS-CoV-2; acute pancreatitis; amylase; lipase.