tetano
Editor, Senior Moderator
Eur J Pediatr
. 2023 Nov 16.
doi: 10.1007/s00431-023-05329-x. Online ahead of print. COVID-19 in hospitalized infants aged under 3 months: multi-center experiences across Turkey
Gülnihan Üstündağ[SUP] 1 [/SUP], Eda Karadag-Oncel[SUP] 2 [/SUP], Nursel Kara-Ulu[SUP] 3 [/SUP], Meltem Polat[SUP] 3 [/SUP], Enes Salı[SUP] 4 [/SUP], Deniz Çakır[SUP] 4 [/SUP], Aslıhan Şahin[SUP] 1 [/SUP], Aybüke Akaslan-Kara[SUP] 5 [/SUP], Pelin Kaçar[SUP] 5 [/SUP], Aylin Dizi Işık[SUP] 6 [/SUP], Pınar Canizci Erdemli[SUP] 6 [/SUP], Sevgi Yaşar Durmuş[SUP] 7 [/SUP], Ahmet Özdemir[SUP] 8 [/SUP], Binnaz Çelik[SUP] 9 [/SUP], Murat Sütçü[SUP] 10 [/SUP], Manolya Kara[SUP] 10 11 [/SUP], Tuğba Kandemir-Gülmez[SUP] 12 [/SUP], Aydın Çelikyurt[SUP] 13 [/SUP], Zühal Ümit[SUP] 14 [/SUP], Hacer Aktürk[SUP] 15 [/SUP], Kamile Arıkan[SUP] 16 [/SUP], Özge Kaba[SUP] 17 [/SUP], Canan Caymaz[SUP] 17 [/SUP], Cihangül Bayhan[SUP] 18 [/SUP], Deniz Aygün[SUP] 19 [/SUP], Döndü Nilay Penezoğlu[SUP] 20 [/SUP], Şilem Özdem Alataş[SUP] 21 [/SUP], Halil Özdemir[SUP] 20 [/SUP], Özden Türel[SUP] 22 [/SUP], Mehtap Akça[SUP] 23 [/SUP], Emel Çelebi-Çongur[SUP] 24 [/SUP], Eda Kepenekli[SUP] 6 [/SUP], Ümit Çelik[SUP] 12 [/SUP], İsmail Zafer Ecevit[SUP] 18 [/SUP], Nurşen Belet[SUP] 21 [/SUP], Nazan Dalgıç[SUP] 24 [/SUP], Nisel Yılmaz[SUP] 25 [/SUP], Dilek Yılmaz[SUP] 1 26 [/SUP], Necdet Kuyucu[SUP] 23 [/SUP], Ergin Çiftçi[SUP] 20 [/SUP]
Affiliations
To investigate coronavirus disease 2019 (COVID-19) in infants aged 0 to 3 months because there is currently a significant gap in the literature on the subject. A cross-sectional study was conducted with the involvement of 19 medical centers across Turkey and 570 infants. The majority of the patients were male (58.2%), and the three most common symptoms were fever (78.2%), cough (44.6%), and feeding intolerance (39.9%). The results showed that a small percentage of infants had positive blood (0.9%) or urine cultures (10.2%). Most infants presented with fever (78.2%). Children without underlying conditions (UCs) had mostly a complicated respiratory course and a normal chest radiography. Significant more positive urine culture rates were observed in infants with fever. A higher incidence of respiratory support requirements and abnormal chest findings were seen in infants with chronic conditions. These infants also had a longer hospital stay than those without chronic conditions. Conclusions: Our study discloses the clinical observations and accompanying bacterial infections found in infants aged under 3 months with COVID-19. These findings can shed light on COVID-19 in infancy for physicians because there is limited clinical evidence available. What is Known: • COVID-19 in infants and older children has been seen more mildly than in adults. • The most common symptoms of COVID-19 in infants are fever and cough, as in older children and adults. COVID-19 should be one of the differential diagnoses in infants with fever. What is New: • Although most infants under three months had fever, the clinical course was uneventful and respiratory complications were rarely observed in healthy children. • Infants with underlying conditions had more frequent respiratory support and abnormal chest radiography and stayed longer in the hospital.
Keywords: Breastfeeding; COVID-19; Children; Clinical presentation; Infants; Neonates.
. 2023 Nov 16.
doi: 10.1007/s00431-023-05329-x. Online ahead of print. COVID-19 in hospitalized infants aged under 3 months: multi-center experiences across Turkey
Gülnihan Üstündağ[SUP] 1 [/SUP], Eda Karadag-Oncel[SUP] 2 [/SUP], Nursel Kara-Ulu[SUP] 3 [/SUP], Meltem Polat[SUP] 3 [/SUP], Enes Salı[SUP] 4 [/SUP], Deniz Çakır[SUP] 4 [/SUP], Aslıhan Şahin[SUP] 1 [/SUP], Aybüke Akaslan-Kara[SUP] 5 [/SUP], Pelin Kaçar[SUP] 5 [/SUP], Aylin Dizi Işık[SUP] 6 [/SUP], Pınar Canizci Erdemli[SUP] 6 [/SUP], Sevgi Yaşar Durmuş[SUP] 7 [/SUP], Ahmet Özdemir[SUP] 8 [/SUP], Binnaz Çelik[SUP] 9 [/SUP], Murat Sütçü[SUP] 10 [/SUP], Manolya Kara[SUP] 10 11 [/SUP], Tuğba Kandemir-Gülmez[SUP] 12 [/SUP], Aydın Çelikyurt[SUP] 13 [/SUP], Zühal Ümit[SUP] 14 [/SUP], Hacer Aktürk[SUP] 15 [/SUP], Kamile Arıkan[SUP] 16 [/SUP], Özge Kaba[SUP] 17 [/SUP], Canan Caymaz[SUP] 17 [/SUP], Cihangül Bayhan[SUP] 18 [/SUP], Deniz Aygün[SUP] 19 [/SUP], Döndü Nilay Penezoğlu[SUP] 20 [/SUP], Şilem Özdem Alataş[SUP] 21 [/SUP], Halil Özdemir[SUP] 20 [/SUP], Özden Türel[SUP] 22 [/SUP], Mehtap Akça[SUP] 23 [/SUP], Emel Çelebi-Çongur[SUP] 24 [/SUP], Eda Kepenekli[SUP] 6 [/SUP], Ümit Çelik[SUP] 12 [/SUP], İsmail Zafer Ecevit[SUP] 18 [/SUP], Nurşen Belet[SUP] 21 [/SUP], Nazan Dalgıç[SUP] 24 [/SUP], Nisel Yılmaz[SUP] 25 [/SUP], Dilek Yılmaz[SUP] 1 26 [/SUP], Necdet Kuyucu[SUP] 23 [/SUP], Ergin Çiftçi[SUP] 20 [/SUP]
Affiliations
- PMID: 37971516
- DOI: 10.1007/s00431-023-05329-x
To investigate coronavirus disease 2019 (COVID-19) in infants aged 0 to 3 months because there is currently a significant gap in the literature on the subject. A cross-sectional study was conducted with the involvement of 19 medical centers across Turkey and 570 infants. The majority of the patients were male (58.2%), and the three most common symptoms were fever (78.2%), cough (44.6%), and feeding intolerance (39.9%). The results showed that a small percentage of infants had positive blood (0.9%) or urine cultures (10.2%). Most infants presented with fever (78.2%). Children without underlying conditions (UCs) had mostly a complicated respiratory course and a normal chest radiography. Significant more positive urine culture rates were observed in infants with fever. A higher incidence of respiratory support requirements and abnormal chest findings were seen in infants with chronic conditions. These infants also had a longer hospital stay than those without chronic conditions. Conclusions: Our study discloses the clinical observations and accompanying bacterial infections found in infants aged under 3 months with COVID-19. These findings can shed light on COVID-19 in infancy for physicians because there is limited clinical evidence available. What is Known: • COVID-19 in infants and older children has been seen more mildly than in adults. • The most common symptoms of COVID-19 in infants are fever and cough, as in older children and adults. COVID-19 should be one of the differential diagnoses in infants with fever. What is New: • Although most infants under three months had fever, the clinical course was uneventful and respiratory complications were rarely observed in healthy children. • Infants with underlying conditions had more frequent respiratory support and abnormal chest radiography and stayed longer in the hospital.
Keywords: Breastfeeding; COVID-19; Children; Clinical presentation; Infants; Neonates.