tetano
Editor, Senior Moderator
Eur Rev Med Pharmacol Sci
. 2020 Sep;24(17):9154-9160.
doi: 10.26355/eurrev_202009_22864.
Venous thromboembolism in critically ill patients affected by ARDS related to COVID-19 in Northern-West Italy
Y Longhitano[SUP] 1 [/SUP], F Racca, C Zanza, A Piccioni, A Audo, M Muncinelli, R Santi, D Kozel, C Geraci, M Taverna, V Bonato, F Cassini, F Franceschi
Affiliations
Abstract
Objective: Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and has subsequently spread worldwide. An association between increased venous thromboembolism in patients with pneumonia-related to COVID-19 has not yet been well described.
Patients and methods: We aimed to illustrate cases of pulmonary thromboembolism in patients with acute respiratory distress syndrome related to COVID-19 treated in our intensive care unit. The medical records of patients affected by COVID-19 with acute respiratory distress syndrome in our institute from 1/3/2020 to 31/3/2020 were retrospectively reviewed.
Results: Our center registered a high prevalence of thromboembolic events among 62 patients affected by acute respiratory distress syndrome related to COVID-19 despite a regular antithrombotic prophylaxis. Out of these, 32 patients were transferred to other hospitals, and 30 were treated in our center. Venous thromboembolism was registered in 12 (19.3%) cases. In particular, 11 diagnoses of pulmonary embolism and 1 diagnosis of deep vein thrombosis were formulated. We described a case series of venous thromboembolism in nine patients treated in our Intensive Care Unit (ICU). Main pulmonary arteries were always involved in these patients. None of them died.
Conclusions: In conclusion, critically ill patients with ARDS related to COVID-19 may have an increased risk of VTE that could be a leading cause of mortality. These patients require a high index of clinical suspicion and an accurate diagnostic approach, in order to immediately start an appropriate anticoagulant treatment.
. 2020 Sep;24(17):9154-9160.
doi: 10.26355/eurrev_202009_22864.
Venous thromboembolism in critically ill patients affected by ARDS related to COVID-19 in Northern-West Italy
Y Longhitano[SUP] 1 [/SUP], F Racca, C Zanza, A Piccioni, A Audo, M Muncinelli, R Santi, D Kozel, C Geraci, M Taverna, V Bonato, F Cassini, F Franceschi
Affiliations
- PMID: 32965007
- DOI: 10.26355/eurrev_202009_22864
Abstract
Objective: Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and has subsequently spread worldwide. An association between increased venous thromboembolism in patients with pneumonia-related to COVID-19 has not yet been well described.
Patients and methods: We aimed to illustrate cases of pulmonary thromboembolism in patients with acute respiratory distress syndrome related to COVID-19 treated in our intensive care unit. The medical records of patients affected by COVID-19 with acute respiratory distress syndrome in our institute from 1/3/2020 to 31/3/2020 were retrospectively reviewed.
Results: Our center registered a high prevalence of thromboembolic events among 62 patients affected by acute respiratory distress syndrome related to COVID-19 despite a regular antithrombotic prophylaxis. Out of these, 32 patients were transferred to other hospitals, and 30 were treated in our center. Venous thromboembolism was registered in 12 (19.3%) cases. In particular, 11 diagnoses of pulmonary embolism and 1 diagnosis of deep vein thrombosis were formulated. We described a case series of venous thromboembolism in nine patients treated in our Intensive Care Unit (ICU). Main pulmonary arteries were always involved in these patients. None of them died.
Conclusions: In conclusion, critically ill patients with ARDS related to COVID-19 may have an increased risk of VTE that could be a leading cause of mortality. These patients require a high index of clinical suspicion and an accurate diagnostic approach, in order to immediately start an appropriate anticoagulant treatment.