Giuseppe
Emeritus
Effectiveness of trivalent seasonal and monovalent influenza A(H1N1)2009 vaccines in population with major chronic conditions of Navarre, Spain ... (Euro Surveill., abstract, edited)
[Source: Eurosurveillance, full text: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19799">Eurosurveillance - View Article</cite>. Abstract, edited.]
Eurosurveillance, Volume 16, Issue 7, 17 February 2011
Surveillance and outbreak reports
Effectiveness of trivalent seasonal and monovalent influenza A(H1N1)2009 vaccines in population with major chronic conditions of Navarre, Spain: 2010/11 mid-season analysis
J Castilla 1,2, J Mor?n 3, V Mart?nez-Artola 4, G Reina 5, I Mart?nez-Baz 1,2, M Garc?a Cenoz 1,2, N Alvarez 6, F Irisarri 1,2, M Arriazu 1,2, F El?a 3, E Salcedo 4
1. Instituto de Salud P?blica de Navarra (Public Health Institute of Navarre), Pamplona, Spain
2. CIBER de Epidemiolog?a y Salud P?blica (Biomedical Research Network of Epidemiology and Public Health)
3. Direcci?n de Atenci?n Primaria, Servicio Navarro de Salud (Primary Health Care Department), Pamplona, Spain
4. Complejo Hospitalario de Navarra (Navarre Hospital Complex), Pamplona, Spain
5. Cl?nica Universidad de Navarra (University Clinic of Navarra), Pamplona, Spain
6. Servicio Navarro de Salud (Navarre Health Service), Pamplona, Spain
Citation style for this article: Castilla J, Mor?n J, Mart?nez-Artola V, Reina G, Mart?nez-Baz I, Garc?a Cenoz M, Alvarez N, Irisarri F, Arriazu M, El?a F, Salcedo E. Effectiveness of trivalent seasonal and monovalent influenza A(H1N1)2009 vaccines in population with major chronic conditions of Navarre, Spain: 2010/11 mid-season analysis. Euro Surveill. 2011;16(7)
ii=19799. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19799
Date of submission: 03 February 2011
We defined a cohort of people with major chronic conditions (152,585 subjects) in Navarre, Spain, using electronic records from physicians, to obtain 2010/11 mid-season estimates of influenza vaccine effectiveness. The adjusted estimates of the effectiveness of the 2010/11 trivalent influenza vaccine were 31% (95% confidence interval (CI): 20?40%) in preventing medically attended influenza-like illness, and 58% (95% CI: 11?80%) in preventing laboratory-confirmed influenza. Having received the monovalent influenza A(H1N1)2009 vaccine in the 2009/10 season had an independent preventive effect against medically attended influenza-like illness (17%, 95% CI: 1?30%), and having received both vaccines had 68% (95% CI: 23?87%) effectiveness in preventing laboratory-confirmed influenza.
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[Source: Eurosurveillance, full text: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19799">Eurosurveillance - View Article</cite>. Abstract, edited.]
Eurosurveillance, Volume 16, Issue 7, 17 February 2011
Surveillance and outbreak reports
Effectiveness of trivalent seasonal and monovalent influenza A(H1N1)2009 vaccines in population with major chronic conditions of Navarre, Spain: 2010/11 mid-season analysis
J Castilla 1,2, J Mor?n 3, V Mart?nez-Artola 4, G Reina 5, I Mart?nez-Baz 1,2, M Garc?a Cenoz 1,2, N Alvarez 6, F Irisarri 1,2, M Arriazu 1,2, F El?a 3, E Salcedo 4
1. Instituto de Salud P?blica de Navarra (Public Health Institute of Navarre), Pamplona, Spain
2. CIBER de Epidemiolog?a y Salud P?blica (Biomedical Research Network of Epidemiology and Public Health)
3. Direcci?n de Atenci?n Primaria, Servicio Navarro de Salud (Primary Health Care Department), Pamplona, Spain
4. Complejo Hospitalario de Navarra (Navarre Hospital Complex), Pamplona, Spain
5. Cl?nica Universidad de Navarra (University Clinic of Navarra), Pamplona, Spain
6. Servicio Navarro de Salud (Navarre Health Service), Pamplona, Spain
Citation style for this article: Castilla J, Mor?n J, Mart?nez-Artola V, Reina G, Mart?nez-Baz I, Garc?a Cenoz M, Alvarez N, Irisarri F, Arriazu M, El?a F, Salcedo E. Effectiveness of trivalent seasonal and monovalent influenza A(H1N1)2009 vaccines in population with major chronic conditions of Navarre, Spain: 2010/11 mid-season analysis. Euro Surveill. 2011;16(7)
ii=19799. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19799Date of submission: 03 February 2011
We defined a cohort of people with major chronic conditions (152,585 subjects) in Navarre, Spain, using electronic records from physicians, to obtain 2010/11 mid-season estimates of influenza vaccine effectiveness. The adjusted estimates of the effectiveness of the 2010/11 trivalent influenza vaccine were 31% (95% confidence interval (CI): 20?40%) in preventing medically attended influenza-like illness, and 58% (95% CI: 11?80%) in preventing laboratory-confirmed influenza. Having received the monovalent influenza A(H1N1)2009 vaccine in the 2009/10 season had an independent preventive effect against medically attended influenza-like illness (17%, 95% CI: 1?30%), and having received both vaccines had 68% (95% CI: 23?87%) effectiveness in preventing laboratory-confirmed influenza.
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