Giuseppe
Emeritus
[Source: Eurosurveillance, full text: (LINK). Abstract, edited.]
J E Fielding (
)<SUP>1</SUP><SUP>,2</SUP>, K A Grant<SUP>1</SUP>, T Tran<SUP>1</SUP>, H A Kelly<SUP>1</SUP><SUP>,2</SUP>
Citation style for this article: Fielding JE, Grant KA, Tran T, Kelly HA. Moderate influenza vaccine effectiveness in Victoria, Australia, 2011. Euro Surveill. 2012;17(11)
ii=20115. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20115
Date of submission: 04 January 2012 <HR>We used a sentinel general practitioner (GP) network to conduct surveillance for laboratory-confirmed influenza amongst patients presenting with influenza-like illness (ILI) in Victoria, Australia in 2011. The test-negative variation of the case control study design was used to estimate effectiveness for seasonal trivalent influenza vaccine. Cases and controls were ILI patients that tested positive and negative for influenza, respectively. Vaccination status was recorded by GPs and vaccine effectiveness (VE) was calculated as (1-adjusted odds ratio)x100%. There were 529 patients included in the study, of which 29% were influenza-positive. Twelve percent of study participants were reported as vaccinated, 6% of cases and 15% of controls. Adjusted VE against all influenza was 56%, but not statistically significant. There was generally little variation in VE estimates when stratified by virus type and subtype, which is consistent with good matches between circulating strains and the vaccine strains. The VE was higher among adults of working age than among children.
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Eurosurveillance, Volume 17, Issue 11, 15 March 2012
Surveillance and outbreak reports
Moderate influenza vaccine effectiveness in Victoria, Australia, 2011
Surveillance and outbreak reports
Moderate influenza vaccine effectiveness in Victoria, Australia, 2011
J E Fielding (
- Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia
- National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia
Citation style for this article: Fielding JE, Grant KA, Tran T, Kelly HA. Moderate influenza vaccine effectiveness in Victoria, Australia, 2011. Euro Surveill. 2012;17(11)
ii=20115. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20115 Date of submission: 04 January 2012 <HR>We used a sentinel general practitioner (GP) network to conduct surveillance for laboratory-confirmed influenza amongst patients presenting with influenza-like illness (ILI) in Victoria, Australia in 2011. The test-negative variation of the case control study design was used to estimate effectiveness for seasonal trivalent influenza vaccine. Cases and controls were ILI patients that tested positive and negative for influenza, respectively. Vaccination status was recorded by GPs and vaccine effectiveness (VE) was calculated as (1-adjusted odds ratio)x100%. There were 529 patients included in the study, of which 29% were influenza-positive. Twelve percent of study participants were reported as vaccinated, 6% of cases and 15% of controls. Adjusted VE against all influenza was 56%, but not statistically significant. There was generally little variation in VE estimates when stratified by virus type and subtype, which is consistent with good matches between circulating strains and the vaccine strains. The VE was higher among adults of working age than among children.