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Eurosurv. Duration of infectiousness and correlation with RT-PCR cycle threshold values in cases of COVID-19, England, January to May 2020

tetano

tetano

Editor, Senior Moderator
  • Duration of infectiousness and correlation with RT-PCR cycle threshold values in cases of COVID-19, England, January to May 2020
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  • Anika Singanayagam[SUP]1,2[/SUP], Monika Patel[SUP]1,2[/SUP] , Andre Charlett[SUP]3[/SUP] , Jamie Lopez Bernal[SUP]4[/SUP] , Vanessa Saliba[SUP]4[/SUP] , Joanna Ellis[SUP]1[/SUP] , Shamez Ladhani[SUP]4[/SUP] , Maria Zambon[SUP]1[/SUP] , Robin Gopal[SUP]1[/SUP]
Severe acute respiratory syndrome coronavirus 2 viral load in the upper respiratory tract peaks around symptom onset and infectious virus persists for 10 days in mild-to-moderate coronavirus disease (n = 324 samples analysed). RT-PCR cycle threshold (Ct) values correlate strongly with cultivable virus. Probability of culturing virus declines to 8% in samples with Ct > 35 and to 6% 10 days after onset; it is similar in asymptomatic and symptomatic persons. Asymptomatic persons represent a source of transmissible virus.


full article

https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.32.2001483#html_fulltext
 
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