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Evaluation of the New World Health Organization Case Definition of Severe Acute Respiratory Infection for Influenza Surveillance During the Peak Weeks

tetano

Editor, Senior Moderator
J Pediatric Infect Dis Soc. 2016 Aug 5. pii: piw044. [Epub ahead of print]
[h=1]Evaluation of the New World Health Organization Case Definition of Severe Acute Respiratory Infection for Influenza Surveillance During the Peak Weeks of Two Influenza Seasons in Quebec, Canada.[/h] Amini R[SUP]1[/SUP], Gilca R[SUP]2[/SUP], Douville-Fradet M[SUP]3[/SUP], Boulianne N[SUP]3[/SUP], De Serres G[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] During the peak of the 2012-2013 and 2014-2015 influenza seasons in Quebec, Canada, the sensitivity of the new World Health Organization (WHO) case definition of severe acute respiratory infection (SARI) in <5-year-old children was 65% for polymerase chain reaction-confirmed influenza and 79% for other respiratory viruses (ORVs), whereas its specificity and positive predictive value were approximately 2- and 4-fold lower for influenza than ORVs (25% vs 40% and 18% vs 76%, respectively). The use of the WHO SARI definition for influenza surveillance in children should be interpreted with caution according to the specific surveillance goals.
? The Author 2016. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.


[h=4]KEYWORDS:[/h] SARI case definition; influenza; other respiratory viruses; positive predictive value; sensitivity

PMID: 27496537 DOI: 10.1093/jpids/piw044
[PubMed - as supplied by publisher]
 
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