tetano
Editor, Senior Moderator
Pathogens. 2019 Sep 25;8(4). pii: E163. doi: 10.3390/pathogens8040163. [h=1]Evidence of the Presence of Low Pathogenic Avian Influenza A Viruses in Wild Waterfowl in 2018 in South Africa.[/h]
Poen MJ[SUP]1[/SUP], Fouchier RAM[SUP]2[/SUP], Webby RJ[SUP]3[/SUP], Webster RG[SUP]4[/SUP], El Zowalaty ME[SUP]5,[/SUP][SUP]6[/SUP].
[h=3]Author information[/h] 1 Department of Viroscience, Erasmus Medical Center, Dr. Molewaterplein 50, 3015GE Rotterdam, The Netherlands. m.poen@erasmusmc.nl. 2 Department of Viroscience, Erasmus Medical Center, Dr. Molewaterplein 50, 3015GE Rotterdam, The Netherlands. r.fouchier@erasmusmc.nl. 3 Division of Virology, Department of Infectious Diseases, Center of Excellence for Influenza Research and Surveillance (CEIRS), St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Richard.webby@stjude.org. 4 Division of Virology, Department of Infectious Diseases, Center of Excellence for Influenza Research and Surveillance (CEIRS), St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Robert.webster@stjude.org. 5 Division of Virology, Department of Infectious Diseases, Center of Excellence for Influenza Research and Surveillance (CEIRS), St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. elzow005@gmail.com. 6 Virology and Microbiology Research Group, Department of Pharmacy, City University College of Ajman, Sheikh Amaar Road, Al Tallah 2, P.O. Box 18484 Ajman, United Arab Emirates. elzow005@gmail.com.
[h=3]Abstract[/h] Avian influenza viruses are pathogens of global concern to both animal and human health. Wild birds are the natural reservoir of avian influenza viruses and facilitate virus transport over large distances. Surprisingly, limited research has been performed to determine avian influenza host species and virus dynamics in wild birds on the African continent, including South Africa. This study described the first wild bird surveillance efforts for influenza A viruses in KwaZulu-Natal Province in South Africa after the 2017/2018 outbreak with highly pathogenic avian influenza virus H5N8 in poultry. A total of 550 swab samples from 278 migratory waterfowl were tested using real-time RT-PCR methods. Two samples (0.7%) were positive for avian influenza virus based on the matrix gene real-time RT-PCR but were negative for the hemagglutinin subtypes H5 and H7. Unfortunately, no sequence information or viable virus could be retrieved from the samples. This study shows that avian influenza viruses are present in the South African wild bird population, emphasizing the need for more extensive surveillance studies to determine the South African avian influenza gene pool and relevant local host species.
[h=4]KEYWORDS:[/h] South Africa; avian influenza; epidemiology; influenza A virus; migratory waterfowl; real-time RT-PCR; surveillance; wild birds; zoonosis
PMID: 31557802 DOI: 10.3390/pathogens8040163
Free full text
Poen MJ[SUP]1[/SUP], Fouchier RAM[SUP]2[/SUP], Webby RJ[SUP]3[/SUP], Webster RG[SUP]4[/SUP], El Zowalaty ME[SUP]5,[/SUP][SUP]6[/SUP].
[h=3]Author information[/h] 1 Department of Viroscience, Erasmus Medical Center, Dr. Molewaterplein 50, 3015GE Rotterdam, The Netherlands. m.poen@erasmusmc.nl. 2 Department of Viroscience, Erasmus Medical Center, Dr. Molewaterplein 50, 3015GE Rotterdam, The Netherlands. r.fouchier@erasmusmc.nl. 3 Division of Virology, Department of Infectious Diseases, Center of Excellence for Influenza Research and Surveillance (CEIRS), St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Richard.webby@stjude.org. 4 Division of Virology, Department of Infectious Diseases, Center of Excellence for Influenza Research and Surveillance (CEIRS), St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Robert.webster@stjude.org. 5 Division of Virology, Department of Infectious Diseases, Center of Excellence for Influenza Research and Surveillance (CEIRS), St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. elzow005@gmail.com. 6 Virology and Microbiology Research Group, Department of Pharmacy, City University College of Ajman, Sheikh Amaar Road, Al Tallah 2, P.O. Box 18484 Ajman, United Arab Emirates. elzow005@gmail.com.
[h=3]Abstract[/h] Avian influenza viruses are pathogens of global concern to both animal and human health. Wild birds are the natural reservoir of avian influenza viruses and facilitate virus transport over large distances. Surprisingly, limited research has been performed to determine avian influenza host species and virus dynamics in wild birds on the African continent, including South Africa. This study described the first wild bird surveillance efforts for influenza A viruses in KwaZulu-Natal Province in South Africa after the 2017/2018 outbreak with highly pathogenic avian influenza virus H5N8 in poultry. A total of 550 swab samples from 278 migratory waterfowl were tested using real-time RT-PCR methods. Two samples (0.7%) were positive for avian influenza virus based on the matrix gene real-time RT-PCR but were negative for the hemagglutinin subtypes H5 and H7. Unfortunately, no sequence information or viable virus could be retrieved from the samples. This study shows that avian influenza viruses are present in the South African wild bird population, emphasizing the need for more extensive surveillance studies to determine the South African avian influenza gene pool and relevant local host species.
[h=4]KEYWORDS:[/h] South Africa; avian influenza; epidemiology; influenza A virus; migratory waterfowl; real-time RT-PCR; surveillance; wild birds; zoonosis
PMID: 31557802 DOI: 10.3390/pathogens8040163
Free full text